Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL328633 | 0.90 | STING1 (0.36) | STING1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL17521943 | 0.82 | STING1 (0.33) | STING1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL16751457 | 0.82 | LMNA (0.36) | STING1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6895085 | 0.82 | EPHX2 (0.35) | STING1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL26192490 | 0.82 | GAA (0.36) | STING1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL25334575 | 0.82 | ALDH1A1 (0.41) | STING1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL21983370 | 0.82 | GAA (0.36) | STING1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL16334546 | 0.81 | STING1 (0.36) | STING1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3960043 | 0.81 | GRM4 (0.37) | STING1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL24894291 | 0.79 | FDPS (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8586371-B2 | Optical sensors including surface modified phase-change materials for detection of chemical, biological and explosive compounds | Exelis Inc. (US) | 2013-11-19 | — | — | US | disclosed |
| US-8586371-B2 | Optical sensors including surface modified phase-change materials for detection of chemical, biological and explosive compounds | Exelis Inc. (US) | 2013-11-19 | — | — | US | disclosed |
| US-20110205542-A1 | Optical Sensors Including Surface Modified Phase-Change Materials for Detection of Chemical, Biological and Explosive Compounds | ITT DEFENSE AND ELECTRONICS (US) | 2011-08-25 | — | — | US | disclosed |
| US-20110205542-A1 | Optical Sensors Including Surface Modified Phase-Change Materials for Detection of Chemical, Biological and Explosive Compounds | ITT DEFENSE AND ELECTRONICS (US) | 2011-08-25 | — | — | US | disclosed |