Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL328633 | 0.92 | STING1 (0.36) | EPHX2STING1HDAC8HDAC1HDAC2 | |
| SCHEMBL24894291 | 0.89 | FDPS (0.36) | TSHRTDP1 | |
| SCHEMBL25334575 | 0.89 | ALDH1A1 (0.41) | EPHX2STING1TSHRHDAC8HDAC1 | |
| SCHEMBL22096420 | 0.86 | STING1 (0.31) | EPHX2STING1 | |
| SCHEMBL17521943 | 0.85 | STING1 (0.33) | EPHX2STING1HDAC8HDAC1HDAC2 | |
| SCHEMBL21983370 | 0.85 | GAA (0.36) | EPHX2STING1HDAC8HDAC1HDAC2 | |
| SCHEMBL16751457 | 0.85 | LMNA (0.36) | EPHX2STING1HDAC8HDAC1HDAC2 | |
| SCHEMBL26192490 | 0.85 | GAA (0.36) | EPHX2STING1HDAC8HDAC1HDAC2 | |
| SCHEMBL23223933 | 0.84 | EPHX2 (0.37) | EPHX2STING1TSHRHDAC8HDAC1 | |
| SCHEMBL12348352 | 0.82 | STING1 (0.34) | EPHX2STING1HDAC8HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1005450-B1 | METHOD OF UTILIZING ISOCYANATE LINKAGES FOR FORMING MULTI-TIER CASCADE POLYMERS | UNIV SOUTH FLORIDA (US) | 2004-08-04 | — | — | EP | disclosed |
| US-5773551-A | Method of utilizing isocyanate linkages for forming multi-tier cascade polymers | UNIVERSITY OF SOUTH FLORIDA (US) | 1998-06-30 | — | — | US | disclosed |