SCHEMBL12349338

SCHEMBL12349338

O=S1(=O)c2ccccc2N(CC[Si](CCN2c3ccccc3S(=O)(=O)c3ccccc32)(c2ccccc2)c2ccccc2)c2ccccc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 2/20 0.54
LMNA P02545 6/20 0.49
THRB P10828 1/20 0.49
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
TP53 P04637 3/20 0.46
MAPT P10636 5/20 0.45
POLB P06746 1/20 0.45
HTR1A P08908 1/20 0.43
HTR2A P28223 1/20 0.43
HTR7 P34969 1/20 0.43
HTR6 P50406 1/20 0.43
HDAC1 Q13547 2/20 0.40
HDAC6 Q9UBN7 2/20 0.40
HDAC3 O15379 1/20 0.37
TUBB4A P04350 1/20 0.37
TUBB P07437 1/20 0.37
TUBA3C P0DPH7 1/20 0.37
HDAC4 P56524 1/20 0.37
TUBA1B P68363 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12349337 0.87 RXFP1 (0.54) RXFP1LMNATHRBMEN1KMT2A
SCHEMBL12349341 0.83 RXFP1 (0.56) RXFP1LMNATHRBMEN1KMT2A
SCHEMBL12349334 0.80 RXFP1 (0.53) RXFP1LMNATHRBMEN1KMT2A
SCHEMBL14281166 0.77 RXFP1 (0.61) RXFP1LMNATHRBMEN1KMT2A
SCHEMBL12349342 0.74 RXFP1 (0.41) RXFP1LMNATHRBMEN1KMT2A
SCHEMBL14281167 0.73 RXFP1 (0.66) RXFP1LMNATHRBMEN1KMT2A
SCHEMBL12349343 0.72 MAPT (0.46) RXFP1LMNATHRBMEN1KMT2A
SCHEMBL12349344 0.70 POLB (0.44) RXFP1LMNATHRBMEN1KMT2A
SCHEMBL4307189 0.70 RXFP1 (0.61) RXFP1LMNATHRBMEN1KMT2A
SCHEMBL30433630 0.70 RXFP1 (0.61) RXFP1LMNATHRBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7989091-B2 Silanes containing phenothiazine-S-oxide or phenothiazine-S,S-dioxide groups and the use thereof in OLEDs BASF SE (DE) 2011-08-02 US disclosed
US-20100187980-A1 SILANES CONTAINING PHENOTHIAZINE-S-OXIDE OR PHENOTHIAZINE-S,S-DIOXIDE GROUPS AND THE USE THEREOF IN OLEDS BASF SE (DE) 2010-07-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100187980-A1 SILANES CONTAINING PHENOTHIAZINE-S-OXIDE OR PHENOTHIAZINE-S,S-DIOXIDE GROUPS AND THE USE THEREOF IN OLEDS OPRD1, PPID, PLOD2 RXFP1 4373/4885LMNA 2054/4885THRB 1946/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.