Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13616973 | 0.93 | POLB (0.33) | LMNAPOLBAPEX1HTTTDP1 | |
| SCHEMBL13911611 | 0.88 | LMNA (0.39) | LMNAPOLBAPEX1HTTTDP1 | |
| SCHEMBL12349801 | 0.87 | TAAR1 (0.40) | LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15369481 | 0.85 | LMNA (0.42) | LMNAPOLBAPEX1HTTTDP1 | |
| SCHEMBL12349788 | 0.83 | HPGD (0.35) | LMNAHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL13616974 | 0.82 | PLAAT3 (0.40) | POLBHTTTDP1KDM4EMEN1 | |
| SCHEMBL3478200 | 0.81 | TSHR (0.46) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL12349800 | 0.81 | TRPV1 (0.37) | AKR1B10AKR1B1 | |
| SCHEMBL3478409 | 0.78 | TSHR (0.49) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL148938 | 0.75 | LMNA (0.60) | LMNAPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190467-A1 | Biological Polysiloxanes | VISION CRC LIMITED (AU) | 2011-08-04 | — | — | US | disclosed |