Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 1/20 | 0.40 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.40 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.40 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12349788 | 0.92 | HPGD (0.35) | PLAAT3PLAAT5PLAAT2PLAAT4MTNR1A | |
| SCHEMBL12349763 | 0.91 | PLAAT3 (0.42) | PLAAT3PLAAT5PLAAT2PLAAT4MTNR1A | |
| SCHEMBL12349801 | 0.89 | TAAR1 (0.40) | MTNR1AMTNR1BMAPTL3MBTL1 | |
| SCHEMBL13616987 | 0.88 | ALOX5 (0.42) | PLAAT3PLAAT5PLAAT2PLAAT4MTNR1A | |
| SCHEMBL12349861 | 0.86 | ADRB2 (0.39) | PLAAT3PLAAT5PLAAT2PLAAT4MTNR1A | |
| SCHEMBL12349782 | 0.82 | LMNA (0.36) | HTTPOLBKDM4EMEN1KMT2A | |
| SCHEMBL12349758 | 0.78 | PLAAT3 (0.47) | PLAAT3PLAAT5PLAAT2PLAAT4MTNR1A | |
| SCHEMBL13616973 | 0.77 | POLB (0.33) | HTTPOLBTDP1 | |
| SCHEMBL12349785 | 0.76 | MGLL (0.36) | MTNR1AMTNR1BALDH1A1HTTPOLB | |
| SCHEMBL12349787 | 0.74 | PTGS1 (0.60) | ALDH1A1HTTPOLBKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090276042-A1 | Biological Polysiloxanes | VISION CRC LIMITED (AU) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090276042-A1 | Biological Polysiloxanes | PBK, B2M, CD79B | PLAAT3 2855/4885PLAAT5 3354/4885PLAAT2 3659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.