Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12349782 | 0.93 | LMNA (0.36) | POLBAPEX1HTTTDP1LMNA | |
| SCHEMBL13911611 | 0.83 | LMNA (0.39) | POLBAPEX1HTTTDP1LMNA | |
| SCHEMBL15369481 | 0.81 | LMNA (0.42) | POLBAPEX1HTTTDP1LMNA | |
| SCHEMBL12349801 | 0.81 | TAAR1 (0.40) | LMNANPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL12349788 | 0.77 | HPGD (0.35) | HTTLMNASMN1; SMN2 | |
| SCHEMBL13616974 | 0.77 | PLAAT3 (0.40) | POLBHTTTDP1 | |
| SCHEMBL3478200 | 0.75 | TSHR (0.46) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL12349800 | 0.75 | TRPV1 (0.37) | AKR1B10AKR1B1 | |
| SCHEMBL3478409 | 0.72 | TSHR (0.49) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL148938 | 0.71 | LMNA (0.60) | POLBAPEX1HTTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090276042-A1 | Biological Polysiloxanes | VISION CRC LIMITED (AU) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090276042-A1 | Biological Polysiloxanes | PBK, B2M, CD79B | POLB 1777/4885APEX1 3106/4885HTT 4573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.