SCHEMBL12352113

SCHEMBL12352113

O=c1oc(-c2csc(-c3nc4ccccc4c(=O)o3)n2)nc2ccccc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.58
ALDH1A1 P00352 5/20 0.57
F2 P00734 4/20 0.57
KMT2A Q03164 4/20 0.57
HPGD P15428 3/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
MEN1 O00255 3/20 0.57
C1R P00736 7/20 0.51
KDM4E B2RXH2 4/20 0.51
NPC1 O15118 3/20 0.51
RAB9A P51151 3/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
NPSR1 Q6W5P4 1/20 0.51
PLG P00747 1/20 0.51
KLK1 P06870 1/20 0.51
PRSS1 P07477 1/20 0.51
C1S P09871 1/20 0.51
ATM Q13315 1/20 0.51
RXFP1 Q9HBX9 1/20 0.51
POLB P06746 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL272287 0.79 ELANE (0.81) ELANEALDH1A1F2KMT2AHPGD
SCHEMBL12352110 0.78 ELANE (0.65) ELANEALDH1A1F2KMT2AHPGD
SCHEMBL12352106 0.78 ELANE (0.69) ELANEALDH1A1F2KMT2AHPGD
SCHEMBL13700932 0.78 ELANE (0.59) ELANEALDH1A1F2KMT2AHPGD
SCHEMBL13700924 0.77 ALDH1A1 (0.61) ELANEALDH1A1F2KMT2AHPGD
SCHEMBL13700914 0.77 ELANE (0.58) ELANEALDH1A1F2KMT2AHPGD
SCHEMBL12352156 0.76 ELANE (0.67) ELANEALDH1A1F2KMT2AHPGD
SCHEMBL12352121 0.76 ELANE (0.67) ELANEALDH1A1F2KMT2AHPGD
SCHEMBL13700941 0.76 ELANE (0.71) ELANEALDH1A1F2KMT2AHPGD
SCHEMBL12352120 0.75 ELANE (0.65) ELANEALDH1A1F2KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8541488-B2 Formed resin article and polymer film FUJIFILM CORPORATION (JP) 2013-09-24 US disclosed
US-8541488-B2 Formed resin article and polymer film FUJIFILM CORPORATION (JP) 2013-09-24 US disclosed
US-20110186791-A1 ULTRAVIOLET ABSORBENT COMPOSITION FUJIFILM CORPORATION (JP) 2011-08-04 US disclosed
US-20110186791-A1 ULTRAVIOLET ABSORBENT COMPOSITION FUJIFILM CORPORATION (JP) 2011-08-04 US disclosed
US-20110163284-A1 LIGHTING UNIT COVER FUJIFILM CORPORATION (JP) 2011-07-07 US disclosed
US-20110163284-A1 LIGHTING UNIT COVER FUJIFILM CORPORATION (JP) 2011-07-07 US disclosed
US-20110092619-A1 FORMED RESIN ARTICLE AND POLYMER FILM FUJIFILM CORPORATION (JP) 2011-04-21 US disclosed
US-20110092619-A1 FORMED RESIN ARTICLE AND POLYMER FILM FUJIFILM CORPORATION (JP) 2011-04-21 US disclosed
US-7897761-B2 Heterocyclic compound FUJIFILM CORPORATION (JP) 2011-03-01 US disclosed
US-7897761-B2 Heterocyclic compound FUJIFILM CORPORATION (JP) 2011-03-01 US disclosed
US-20110024701-A1 Ultraviolet Absorbent Composition FUJIFILM CORPORATION (JP) 2011-02-03 US disclosed
US-20110024701-A1 Ultraviolet Absorbent Composition FUJIFILM CORPORATION (JP) 2011-02-03 US disclosed
US-20100004439-A1 Heterocyclic Compound FUJIFLM CORPORATION (JP) 2010-01-07 US disclosed
US-20100004439-A1 Heterocyclic Compound FUJIFLM CORPORATION (JP) 2010-01-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100004439-A1 Heterocyclic Compound PTGER1, CYP1A1, ALOX12 ELANE 1343/4885ALDH1A1 1205/4885F2 56/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.