SCHEMBL12352121

SCHEMBL12352121

O=c1oc(-c2cnc(-c3nc4ccccc4c(=O)o3)cn2)nc2ccccc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.67
F2 P00734 3/20 0.59
C1R P00736 6/20 0.58
ALDH1A1 P00352 6/20 0.58
NPC1 O15118 4/20 0.58
RAB9A P51151 4/20 0.58
KDM4E B2RXH2 4/20 0.58
HPGD P15428 3/20 0.58
KMT2A Q03164 3/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
NPSR1 Q6W5P4 1/20 0.58
PLG P00747 1/20 0.58
KLK1 P06870 1/20 0.58
PRSS1 P07477 1/20 0.58
C1S P09871 1/20 0.58
ATM Q13315 1/20 0.58
RXFP1 Q9HBX9 1/20 0.58
SMN1; SMN2 Q16637 4/20 0.56
MEN1 O00255 2/20 0.56
POLB P06746 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13700937 0.89 ELANE (0.61) ELANEF2C1RALDH1A1NPC1
SCHEMBL13700917 0.86 F2 (0.63) ELANEF2C1RALDH1A1NPC1
SCHEMBL12352108 0.86 ELANE (0.67) ELANEF2C1RALDH1A1NPC1
SCHEMBL272287 0.85 ELANE (0.81) ELANEF2C1RALDH1A1NPC1
SCHEMBL12352120 0.85 ELANE (0.65) ELANEF2C1RALDH1A1NPC1
SCHEMBL12352106 0.84 ELANE (0.69) ELANEF2C1RALDH1A1NPC1
SCHEMBL8203003 0.83 ELANE (0.63) ELANEF2C1RALDH1A1NPC1
SCHEMBL13700941 0.82 ELANE (0.71) ELANEF2C1RALDH1A1NPC1
SCHEMBL13701052 0.81 ELANE (0.46) ELANEF2C1RALDH1A1NPC1
SCHEMBL12352119 0.81 ELANE (0.59) ELANEF2C1RALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210033886-A1 LENS FOR SPECTACLES AND SPECTACLES FUJIFILM CORPORATION (JP) 2021-02-04 US disclosed
US-8541488-B2 Formed resin article and polymer film FUJIFILM CORPORATION (JP) 2013-09-24 US disclosed
US-8541488-B2 Formed resin article and polymer film FUJIFILM CORPORATION (JP) 2013-09-24 US disclosed
US-8304538-B2 Method of producing benzoxazinone-based compound FUJIFILM CORPORATION (JP) 2012-11-06 US disclosed
US-8304538-B2 Method of producing benzoxazinone-based compound FUJIFILM CORPORATION (JP) 2012-11-06 US disclosed
US-20110186791-A1 ULTRAVIOLET ABSORBENT COMPOSITION FUJIFILM CORPORATION (JP) 2011-08-04 US disclosed
US-20110186791-A1 ULTRAVIOLET ABSORBENT COMPOSITION FUJIFILM CORPORATION (JP) 2011-08-04 US disclosed
US-20110163284-A1 LIGHTING UNIT COVER FUJIFILM CORPORATION (JP) 2011-07-07 US disclosed
US-20110163284-A1 LIGHTING UNIT COVER FUJIFILM CORPORATION (JP) 2011-07-07 US disclosed
US-20110092619-A1 FORMED RESIN ARTICLE AND POLYMER FILM FUJIFILM CORPORATION (JP) 2011-04-21 US disclosed
US-7897761-B2 Heterocyclic compound FUJIFILM CORPORATION (JP) 2011-03-01 US disclosed
US-20110024701-A1 Ultraviolet Absorbent Composition FUJIFILM CORPORATION (JP) 2011-02-03 US disclosed
US-20110024701-A1 Ultraviolet Absorbent Composition FUJIFILM CORPORATION (JP) 2011-02-03 US disclosed
US-20110015314-A1 ULTRAVIOLET ABSORBENT AND PRODUCTION METHOD OF THE SAME FUJIFILM CORPORATION (JP) 2011-01-20 US disclosed
US-20110015314-A1 ULTRAVIOLET ABSORBENT AND PRODUCTION METHOD OF THE SAME FUJIFILM CORPORATION (JP) 2011-01-20 US disclosed
US-20100256362-A1 METHOD OF PRODUCING BENZOXAZINONE-BASED COMPOUND FUJIFILM CORPORATION (JP) 2010-10-07 US disclosed
US-20100256362-A1 METHOD OF PRODUCING BENZOXAZINONE-BASED COMPOUND FUJIFILM CORPORATION (JP) 2010-10-07 US disclosed
US-20100004439-A1 Heterocyclic Compound FUJIFLM CORPORATION (JP) 2010-01-07 US disclosed
US-20100004439-A1 Heterocyclic Compound FUJIFLM CORPORATION (JP) 2010-01-07 US disclosed
WO-2009041715-A1 METHOD OF PRODUCING BENZOXAZINONE-BASED COMPOUND FUJIFILM CORPORATION (JP) 2009-04-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110015314-A1 ULTRAVIOLET ABSORBENT AND PRODUCTION METHOD OF THE SAME SLC40A1, F2, SLC19A1 ELANE 3147/4885F2 2/4885C1R 73/4885
US-20100256362-A1 METHOD OF PRODUCING BENZOXAZINONE-BASED COMPOUND SDHA, CYP4X1, SDHB ELANE 2786/4885F2 298/4885C1R 523/4885
US-20100004439-A1 Heterocyclic Compound PTGER1, CYP1A1, ALOX12 ELANE 1343/4885F2 56/4885C1R 959/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.