Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27141132 | 0.97 | RAB9A (0.54) | RAB9AKMT2AMEN1POLBKDM4E | |
| SCHEMBL6477476 | 0.90 | KDM4E (0.58) | RAB9AKMT2AMEN1POLBKDM4E | |
| SCHEMBL2491378 | 0.85 | RAB9A (0.72) | RAB9AKMT2AMEN1POLBKDM4E | |
| SCHEMBL1235256 | 0.84 | LMNA (0.60) | RAB9AKMT2AMEN1POLBKDM4E | |
| SCHEMBL12348717 | 0.83 | HSD17B1 (0.56) | RAB9AKMT2AMEN1POLBKDM4E | |
| SCHEMBL29906326 | 0.83 | CA1 (0.50) | KMT2AMEN1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL497984 | 0.83 | ESRRG (0.56) | RAB9AKMT2AMEN1POLBKDM4E | |
| SCHEMBL6805238 | 0.82 | KDM4E (0.67) | RAB9AKMT2AMEN1POLBKDM4E | |
| SCHEMBL7259715 | 0.82 | APP (0.53) | RAB9AKMT2AMEN1POLBKDM4E | |
| SCHEMBL2550687 | 0.82 | KDM4E (0.72) | KDM4EHPGDNPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4326436-A1 | MOF, MOF LINKERS AND MANUFACTURING METHOD THEREOF | Universiteit Antwerpen (BE) | 2024-02-28 | — | — | EP | disclosed |
| WO-2022223773-A1 | MOF, MOF LINKERS AND MANUFACTURING METHOD THEREOF | UNIVERSITEIT ANTWERPEN (BE) | 2022-10-27 | — | — | WO | disclosed |