Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 2/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19526017 | 0.88 | SMN1; SMN2 (0.32) | PSMB8PSMB5KMT2ASMN1; SMN2 | |
| SCHEMBL25132915 | 0.86 | KMT2A (0.32) | KMT2ASMN1; SMN2 | |
| SCHEMBL14466493 | 0.84 | MGLL (0.34) | PSMB8PSMB5KMT2A | |
| SCHEMBL43576 | 0.81 | PSMB8 (0.35) | PSMB8PSMB5KMT2ASMN1; SMN2 | |
| SCHEMBL21660208 | 0.80 | NOTUM (0.36) | PSMB8PSMB5SMN1; SMN2 | |
| SCHEMBL14948533 | 0.80 | TSHR (0.43) | KMT2ASMN1; SMN2 | |
| SCHEMBL16724697 | 0.80 | MGLL (0.35) | PSMB8PSMB5 | |
| SCHEMBL19751694 | 0.80 | ALDH1A1 (0.39) | PSMB8PSMB5NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL31522720 | 0.79 | PSMB8 (0.34) | PSMB8PSMB5KMT2ASMN1; SMN2 | |
| SCHEMBL70665 | 0.78 | ALDH1A1 (0.43) | PSMB8PSMB5KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9290421-B2 | Hypervalent radioactive astatine or iodine compounds, and preparation methods thereof | Institut National de la Santé de la Recherche Medicalé (FR) | 2016-03-22 | — | — | US | disclosed |
| WO-2011095517-A1 | HYPERVALENT RADIOACTIVE ASTATINE OR IODINE COMPOUNDS, AND PREPARATION METHODS THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2011-08-11 | — | — | WO | disclosed |