Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6358200 | 0.93 | CYP1A2 (0.46) | TSHRLMNAPOLBALDH1A1NOTUM | |
| SCHEMBL17256327 | 0.92 | CYP1A2 (0.44) | TSHRALDH1A1CYP1A2GAACYP4F2 | |
| SCHEMBL14644916 | 0.89 | PSMB8 (0.33) | TSHRLMNA | |
| SCHEMBL43576 | 0.87 | PSMB8 (0.35) | TSHRLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL12060996 | 0.86 | ALDH1A1 (0.41) | LMNAALDH1A1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL141048 | 0.85 | ADRA2A (0.36) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9329901 | 0.85 | DGKA (0.37) | TSHRALDH1A1CYP1A2GAACYP2C19 | |
| SCHEMBL31522720 | 0.85 | PSMB8 (0.34) | LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL18915652 | 0.83 | ALDH1A1 (0.44) | LMNAALDH1A1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL70665 | 0.83 | ALDH1A1 (0.43) | ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170319696-A1 | Derivatized Hyperbranched Polyglycerols | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2017-11-09 | — | — | US | disclosed |
| US-9561278-B2 | Derivatized hyperbranched polyglycerols | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2017-02-07 | — | — | US | disclosed |
| US-20160114040-A1 | Derivatized Hyperbranched Polyglycerols | CENTRE FOR DRUG RESEARCH AND DEVELOPMENT (CA) | 2016-04-28 | — | — | US | disclosed |
| US-9186410-B2 | Derivatized hyperbranched polyglycerols | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2015-11-17 | — | — | US | disclosed |
| US-20140155457-A1 | Method of Relieving, Improving, Preventing or Treating Xerostomia | SUNBIO INC. (KR) | 2014-06-05 | — | — | US | disclosed |
| US-20130122112-A1 | Derivatized Hyperbranched Polyglycerols | CENTRE FOR DRUG RESEARCH AND DEVELOPMENT (CA) | 2013-05-16 | — | — | US | disclosed |
| US-8202963-B2 | Tissue adhesives with modified elasticity | ACTAMAX SURGICAL MATERIALS, LLC (US) | 2012-06-19 | — | — | US | disclosed |
| US-20110269916-A1 | TISSUE ADHESIVES WITH MODIFIED ELASTICITY | ACTAMAX SURGICAL MATERIALS, LLC | 2011-11-03 | — | — | US | disclosed |
| CN-1142775-A | Preparation and use of immunoconjugates | IMMUNOMEDICS INC (US) | 1997-02-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155457-A1 | Method of Relieving, Improving, Preventing or Treating Xerostomia | GLA, LPO, MUC1 | TSHR 1811/4885LMNA 3918/4885POLB 434/4885 |
| US-20160114040-A1 | Derivatized Hyperbranched Polyglycerols | DDOST, UGCG, DAD1 | TSHR 4684/4885LMNA 1086/4885POLB 1960/4885 |
| US-20130122112-A1 | Derivatized Hyperbranched Polyglycerols | DDOST, UGCG, DAD1 | TSHR 4684/4885LMNA 1086/4885POLB 1960/4885 |
| US-20170319696-A1 | Derivatized Hyperbranched Polyglycerols | DDOST, UGCG, DAD1 | TSHR 4684/4885LMNA 1086/4885POLB 1960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.