Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | SCD | O00767 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ILK | Q13418 | 1/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865437 | 0.80 | MAOA (0.58) | MAOAMAOBSCDMAPTRAB9A | |
| SCHEMBL7169922 | 0.78 | KMT2A (0.59) | MAOAMAOBMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL12320017 | 0.77 | SCD (0.49) | SCDMAPTSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL3634489 | 0.76 | HSD17B1 (0.63) | MAOAMAOBSCDMAPTRAB9A | |
| SCHEMBL9548105 | 0.76 | PTGS2 (0.77) | MAPTRAB9ANPC1TP53HPGD | |
| SCHEMBL2708042 | 0.76 | SCN4A (0.71) | MAPTRAB9ASMN1; SMN2NPC1TP53 | |
| Hydrochloric Acid SCHEMBL9547994 | 0.75 | PTGS2 (0.75) | MAPTRAB9ANPC1TP53HPGD | |
| SCHEMBL3086399 | 0.75 | MAPT (0.61) | MAOAMAOBSCDMAPTRAB9A | |
| SCHEMBL7158014 | 0.75 | MAPT (0.64) | MAOAMAOBSCDMAPTRAB9A | |
| SCHEMBL12353721 | 0.75 | SMN1; SMN2 (0.45) | RAB9ASMN1; SMN2HPGDALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351749-A1 | CARBAMATE COMPOUND OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2011-08-03 | — | — | EP | disclosed |