Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.59 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.58 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.58 |
| ▸ | SCD | O00767 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.58 |
| ▸ | CASP2 | P42575 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8403873 | 0.86 | HSD17B1 (0.67) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL3634489 | 0.86 | HSD17B1 (0.63) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL3086399 | 0.85 | MAPT (0.61) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL16398809 | 0.85 | ALDH1A1 (0.63) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21945012 | 0.85 | ALDH1A1 (0.56) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2762136 | 0.84 | MAPT (0.67) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21945149 | 0.84 | ALDH1A1 (0.55) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL730623 | 0.83 | ALDH1A1 (0.65) | ALDH1A1CYP1A2CYP3A4CYP2C19DYRK1A | |
| SCHEMBL31410 | 0.82 | HSD17B1 (0.73) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL20832544 | 0.82 | ALDH1A1 (0.67) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110292948-B | Application of imines-functionalized imidazole chloride salt as catalyst in preparation of aromatic heterocyclic formate compounds | 苏州大学 | 2022-02-25 | — | — | CN | disclosed |
| EP-1328514-A1 | AMIDE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002034718-A1 | AMIDE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2002-05-02 | — | — | WO | disclosed |