Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | BCL9 | O00512 | 1/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21097206 | 1.00 | HTR2A (0.61) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL763026 | 0.94 | HTR2A (0.64) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL2597348 | 0.88 | HTR2A (0.64) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL14985547 | 0.87 | HTR2A (0.56) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL21097202 | 0.87 | HTR2A (0.56) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL13108205 | 0.87 | HTR2A (0.56) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL7411825 | 0.86 | HTR2A (0.61) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL21097372 | 0.85 | HTR2A (0.55) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL27355874 | 0.84 | HTR2A (0.60) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL15760497 | 0.83 | HTR2A (0.58) | HTR2ABCL9CTNNB1GAAMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150258206-A1 | GLYCEROL LINKED PEGYLATED SUGARS AND GLYCOPEPTIDES | NOVO NORDISK AS (DK) | 2015-09-17 | — | — | US | disclosed |
| US-8911967-B2 | One pot desialylation and glycopegylation of therapeutic peptides | NOVO NORDISK A/S (DK) | 2014-12-16 | — | — | US | disclosed |
| US-8828373-B2 | Polyalkylene glycol derivative and modified bio-related substance | NOF CORPORATION (JP) | 2014-09-09 | — | — | US | disclosed |
| US-20130137157-A1 | GLYCOPEGYLATED FACTOR VII AND FACTOR VIIA | NOVO NORDISK A/S (DK) | 2013-05-30 | — | — | US | disclosed |
| US-8003117-B2 | Purity; polyether containing glycerol backbone capable of being label | NOF CORPORATION (JP) | 2011-08-23 | — | — | US | disclosed |
| US-20100330645-A1 | ONE POT DESIALYLATION AND GLYCOPEGYLATION OF THERAPEUTIC PEPTIDES | NOVO NORDISK A/S (DK) | 2010-12-30 | — | — | US | disclosed |
| US-7851491-B2 | Modified bio-related substance, process for producing the same, and intermediate | NOF CORPORATION (JP) | 2010-12-14 | — | — | US | disclosed |
| US-20100113743-A1 | GLYCOPEGYLATED FACTOR VII AND FACTOR VIIA | NOVO NORDISK A/S (DK) | 2010-05-06 | — | — | US | disclosed |
| US-20100041872-A1 | GLYCEROL LINKED PEGYLATED SUGARS AND GLYCOPEPTIDES | NOVO NORDISK A/S (DK) | 2010-02-18 | — | — | US | disclosed |
| US-20100009902-A1 | Glycoconjugation Using Saccharyl Fragments | NEOSE TECHNOLOGIES, INC. (US) | 2010-01-14 | — | — | US | disclosed |
| US-20090305967-A1 | GLYCOPEGYLATED FACTOR VII AND FACTOR VIIA | NOVO NORDISK A/S (DK) | 2009-12-10 | — | — | US | disclosed |
| US-20090192320-A1 | MODIFIED BIO-RELATED SUBSTANCE, PROCESS FOR PRODUCING THE SAME, AND INTERMEDIATE | NOF CORPORATION (JP) | 2009-07-30 | — | — | US | disclosed |
| US-7524875-B2 | Modified bio-related substance, process for producing the same, and intermediate | NOF CORPORATION (JP) | 2009-04-28 | — | — | US | disclosed |
| US-20080146782-A1 | GLYCEROL LINKED PEGYLATED SUGARS AND GLYCOPEPTIDES | NEOSE TECHNOLOGIES, INC. (US) | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192320-A1 | MODIFIED BIO-RELATED SUBSTANCE, PROCESS FOR PRODUCING THE SAME, AND INTERMEDIATE | BMP1, BMP2, AQP1 | HTR2A 1279/4885BCL9 1047/4885CTNNB1 2292/4885 |
| US-20090305967-A1 | GLYCOPEGYLATED FACTOR VII AND FACTOR VIIA | F7, F13B, F13A1 | HTR2A 4574/4885BCL9 2805/4885CTNNB1 4852/4885 |
| US-20080146782-A1 | GLYCEROL LINKED PEGYLATED SUGARS AND GLYCOPEPTIDES | UGCG, B3GAT3, UGGT1 | HTR2A 4652/4885BCL9 2105/4885CTNNB1 4803/4885 |
| US-20100009902-A1 | Glycoconjugation Using Saccharyl Fragments | B3GAT3, UGGT1, UGCG | HTR2A 4414/4885BCL9 3414/4885CTNNB1 4870/4885 |
| US-20100113743-A1 | GLYCOPEGYLATED FACTOR VII AND FACTOR VIIA | F7, F13B, F13A1 | HTR2A 4574/4885BCL9 2805/4885CTNNB1 4852/4885 |
| US-20100041872-A1 | GLYCEROL LINKED PEGYLATED SUGARS AND GLYCOPEPTIDES | UGCG, B3GAT3, UGGT1 | HTR2A 4652/4885BCL9 2105/4885CTNNB1 4803/4885 |
| US-20150258206-A1 | GLYCEROL LINKED PEGYLATED SUGARS AND GLYCOPEPTIDES | UGCG, B3GAT3, UGGT1 | HTR2A 4652/4885BCL9 2105/4885CTNNB1 4803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.