Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | RGS4 | P49798 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12366238 | 0.92 | DCTPP1 (0.42) | CNR1KDM4EHPGDNPSR1DCTPP1 | |
| SCHEMBL12366212 | 0.92 | CNR1 (0.44) | CNR1KDM4EHPGDNPSR1DCTPP1 | |
| SCHEMBL12366250 | 0.91 | MAPT (0.40) | CNR1MAPTTP53ITGB1ITGA4 | |
| SCHEMBL12366480 | 0.91 | CNR1 (0.42) | CNR1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL12366320 | 0.90 | KDM4E (0.47) | CNR1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL12366308 | 0.90 | RXRA (0.43) | CNR1MAPTKDM4EHPGDDCTPP1 | |
| SCHEMBL12366275 | 0.90 | CFTR (0.42) | CNR1KDM4EHPGDNPSR1DCTPP1 | |
| SCHEMBL12366295 | 0.89 | ITGB1 (0.39) | CNR1MAPTHPGDDCTPP1TP53 | |
| SCHEMBL12366434 | 0.89 | CNR1 (0.42) | CNR1KDM4EHPGDNPSR1DCTPP1 | |
| SCHEMBL12366233 | 0.89 | CNR1 (0.42) | CNR1MAPTKDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998986-B2 | Heterocyclic compounds, in particular N-substituted pyridones for modulating the activity of nuclear receptors | EXELIXIS PATENT COMPANY LLC (US) | 2011-08-16 | — | — | US | disclosed |