Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12366212 | 0.95 | CNR1 (0.44) | DCTPP1CNR1RXRANR1H2NR1H3 | |
| SCHEMBL12366308 | 0.93 | RXRA (0.43) | DCTPP1CNR1RXRANR1H2NR1H3 | |
| SCHEMBL12366320 | 0.93 | KDM4E (0.47) | DCTPP1CNR1RXRANR1H2NR1H3 | |
| SCHEMBL12366275 | 0.93 | CFTR (0.42) | DCTPP1CNR1RXRANR1H2NR1H3 | |
| SCHEMBL12366245 | 0.92 | CNR1 (0.43) | DCTPP1CNR1RXRANR1H2NR1H3 | |
| SCHEMBL12366313 | 0.92 | CNR1 (0.38) | DCTPP1CNR1RXRANR1H2NR1H3 | |
| SCHEMBL12366295 | 0.90 | ITGB1 (0.39) | DCTPP1CNR1HPGDPPARGALDH1A1 | |
| SCHEMBL12366376 | 0.90 | RXRA (0.40) | DCTPP1CNR1RXRAHPGDKDM4E | |
| SCHEMBL12366395 | 0.90 | CCR2 (0.44) | DCTPP1CNR1HPGDKDM4EPPARG | |
| SCHEMBL12366324 | 0.90 | NR1H2 (0.49) | DCTPP1CNR1RXRANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998986-B2 | Heterocyclic compounds, in particular N-substituted pyridones for modulating the activity of nuclear receptors | EXELIXIS PATENT COMPANY LLC (US) | 2011-08-16 | — | — | US | disclosed |