Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.69 |
| ▸ | DRD4 | P21917 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541920 | 0.82 | OPRM1 (1.00) | OPRM1DRD4ALDH1A1SMN1; SMN2GRIN2D | |
| SCHEMBL19931803 | 0.78 | OPRM1 (0.50) | OPRM1DRD4ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1637840 | 0.77 | OPRM1 (0.54) | OPRM1DRD4ALDH1A1SMN1; SMN2CHRM2 | |
| SCHEMBL9966015 | 0.76 | OPRM1 (0.48) | OPRM1DRD4ALDH1A1GRIN2BLMNA | |
| SCHEMBL11738164 | 0.76 | OPRM1 (0.77) | OPRM1DRD4GRIN2DGRIN3BCHRM2 | |
| SCHEMBL19567293 | 0.76 | OPRM1 (0.48) | OPRM1DRD4ALDH1A1LMNASLC6A2 | |
| Hydrochloric Acid SCHEMBL11747049 | 0.75 | OPRM1 (0.74) | OPRM1DRD4GRIN2DGRIN3BCHRM2 | |
| SCHEMBL24119452 | 0.73 | OPRM1 (0.46) | OPRM1DRD4ALDH1A1SMN1; SMN2GRIN2D | |
| SCHEMBL27373100 | 0.73 | OPRM1 (0.46) | OPRM1DRD4CHRM2KCNH2CYP2D6 | |
| SCHEMBL18269494 | 0.72 | AKR1C1 (0.57) | OPRM1DRD4ALDH1A1KCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9649303-B2 | Methods and treatment for allergies and inflammation associated with gastrointestinal diseases | MASTCELL PHARMACEUTICALS, INC. (US) | 2017-05-16 | — | — | US | disclosed |
| US-20140302153-A1 | METHODS AND TREATMENT FOR ALLERGIES AND INFLAMMATION ASSOCIATED WITH GASTROINTESTINAL DISEASES | MASTCELL PHARMACEUTICALS, INC. (US) | 2014-10-09 | — | — | US | disclosed |
| US-20110206659-A1 | METHODS AND TREATMENT FOR ALLERGIES AND INFLAMMATION ASSOCIATED WITH GASTROINTESTINAL DISEASES | MASTCELL PHARMACEUTICALS, INC. | 2011-08-25 | — | — | US | disclosed |
| US-20100166804-A1 | METHODS | MASTCELL PHARMACEUTICALS, INC. | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110206659-A1 | METHODS AND TREATMENT FOR ALLERGIES AND INFLAMMATION ASSOCIATED WITH GASTROINTESTINAL DISEASES | CMA1, HRH2, TPSG1 | OPRM1 2835/4885DRD4 4837/4885ALDH1A1 1293/4885 |
| US-20100166804-A1 | METHODS | CPA3, CMA1, HRH2 | OPRM1 3413/4885DRD4 3986/4885ALDH1A1 2411/4885 |
| US-20140302153-A1 | METHODS AND TREATMENT FOR ALLERGIES AND INFLAMMATION ASSOCIATED WITH GASTROINTESTINAL DISEASES | CMA1, HRH2, TPSG1 | OPRM1 2835/4885DRD4 4837/4885ALDH1A1 1293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.