Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 1.00 |
| ▸ | DRD4 | P21917 | 1/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.53 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11738164 | 0.87 | OPRM1 (0.77) | OPRM1DRD4KCNH2GRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL11747049 | 0.85 | OPRM1 (0.74) | OPRM1DRD4KCNH2GRIN1GRIN2A | |
| SCHEMBL12367138 | 0.82 | OPRM1 (0.69) | OPRM1DRD4KCNH2GRIN1GRIN2A | |
| SCHEMBL24119449 | 0.78 | OPRM1 (0.63) | OPRM1DRD4KCNH2GRIN1GRIN2A | |
| SCHEMBL8931777 | 0.78 | OPRM1 (0.63) | OPRM1DRD4KCNH2GRIN1GRIN2A | |
| SCHEMBL27099783 | 0.78 | OPRM1 (0.63) | OPRM1DRD4KCNH2GRIN1GRIN2A | |
| SCHEMBL13589214 | 0.77 | OPRM1 (0.61) | OPRM1DRD4KCNH2GRIN1GRIN2A | |
| SCHEMBL1205908 | 0.76 | OPRM1 (0.61) | OPRM1DRD4ALDH1A1OPRD1OPRK1 | |
| SCHEMBL14431893 | 0.76 | OPRM1 (0.61) | OPRM1DRD4KCNH2GRIN1GRIN2A | |
| SCHEMBL13713106 | 0.76 | OPRM1 (0.61) | OPRM1DRD4KCNH2CHRM2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527272-B | Synthetic method of tergolian prazan | 西安淳甄新材料有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-113527272-A | Synthesis method of Tegolazan | 西安淳甄新材料有限公司 | 2021-10-22 | — | — | CN | claimed |
| CN-118871429-A | Crystal forms of isochroman compounds | 深圳扬厉医药技术有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-117616023-A | BCL-2 or BCL-2/BCL-XL modulators and uses thereof | 爱新医药科技(香港)有限公司 | 2024-02-27 | — | — | CN | disclosed |
| WO-2023169462-A1 | CRYSTAL FORM OF ISOCHROMAN COMPOUND | 深圳扬厉医药技术有限公司 | 2023-09-14 | — | — | WO | disclosed |
| CN-113527272-B | Synthetic method of tergolian prazan | 西安淳甄新材料有限公司 | 2023-07-21 | — | — | CN | disclosed |
| WO-2022187206-A1 | DUAL-TARGET MU OPIOID AND DOPAMINE D3 RECEPTORS LIGANDS; PREPARATION AND USE THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2022-09-09 | — | — | WO | disclosed |
| CN-110325531-B | Benzenesulfonamides and their use as therapeutic agents | 泽农医药公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114450271-A | Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition | 纽力克斯治疗公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-110352006-B | Picolinamides as fungicides | 美国陶氏益农公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-108290881-B | Therapeutic compounds and methods of use thereof | 健泰科生物技术公司 | 2021-12-07 | — | — | CN | disclosed |
| US-20050261374-A1 | Process for the preparation of prostaglandins and analogues thereof | RESOLUTION CHEMICALS LIMITED | 2005-11-24 | — | — | US | disclosed |
| US-5696050-A | APPLYING TO CROP PLANT, SEED OR SURROUNDING SOIL OR WATER ANTIDOTAL AMOUNT OF PLANT SAFENING AGENT | AMERICAN CYANAMID COMPANY (US) | 1997-12-09 | — | — | US | disclosed |
| EP-0775118-A1 | BENZIMIDAZOLE DERIVATIVES HAVING DOPAMINERGIC ACTIVITY | PFIZER INC. (US) | 1997-05-28 | — | — | EP | disclosed |
| EP-0613618-B1 | Method for safening herbicides in crops using substituted benzopyran and tetrahydronaphthalene compounds | AMERICAN CYANAMID CO (US) | 1997-04-16 | — | — | EP | disclosed |
| EP-0750617-A1 | NOVEL HETEROCYCLIC ETHANOLAMINE DERIVATIVES WITH BETA-ADRENORECEPTOR AGONISTIC ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1997-01-02 | — | — | EP | disclosed |
| US-5516918-A | PLANT SAFTENING AGENTS USING BENZOPYRAN-4-ACETIC ACIDS OR BENZOTHIOPYRAN-4-ACETIC ACIDS | AMERICAN CYANAMID COMPANY (US) | 1996-05-14 | — | — | US | disclosed |
| WO-1995025104-A1 | NOVEL HETEROCYCLIC ETHANOLAMINE DERIVATIVES WITH BETA-ADRENORECEPTOR AGONISTIC ACTIVITY | SMITHKLINE BEECHAM P.L.C. (GB) | 1995-09-21 | — | — | WO | disclosed |
| US-5407897-A | Plant safening agents | AMERICAN CYANAMID COMPANY (US) | 1995-04-18 | — | — | US | disclosed |
| EP-0613618-A1 | Method for safening herbicides in crops using substituted benzopyran and tetrahydronaphthalene compounds | AMERICAN CYANAMID COMPANY (US) | 1994-09-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261374-A1 | Process for the preparation of prostaglandins and analogues thereof | PTGIS, PTGES, PTGES2 | OPRM1 2038/4885DRD4 2626/4885KCNH2 2715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.