Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10000755 | 0.87 | CA1 (0.31) | KMT2ACA1CA2 | |
| SCHEMBL10000757 | 0.80 | FASN (0.32) | — | |
| SCHEMBL10000754 | 0.73 | AKR1B1 (0.36) | HPGDKMT2APOLBALDH1A1KDM4E | |
| SCHEMBL10000756 | 0.73 | PTGS2 (0.37) | PTGS2NPC1RAB9AKMT2APOLB | |
| SCHEMBL12927515 | 0.66 | ALDH1A1 (0.50) | HPGDNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL12744505 | 0.65 | ERBB2 (0.40) | HPGDSMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL21342392 | 0.65 | HPGD (0.75) | HPGDNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6188972 | 0.65 | HPGD (0.56) | HPGDSMN1; SMN2KMT2ALMNAPOLB | |
| SCHEMBL29261236 | 0.64 | POLB (0.40) | HPGDNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL14756447 | 0.64 | ALDH1A1 (0.43) | HPGDNPC1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003824-B2 | Preparation of hydroquinone amide compounds with antioxidant properties | CATALYS SAS (FR) | 2011-08-23 | — | — | US | disclosed |