SCHEMBL12367184

SCHEMBL12367184

Fc1ccc2c3c(cccc13)-c1cc(-c3ccc4c5c(cccc35)-c3c-4c(-c4ccccc4)c4ccccc4c3-c3ccccc3)ccc1-2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.37
PTPN1 P18031 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
MAPT P10636 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MEN1 O00255 1/20 0.36
APAF1 O14727 1/20 0.36
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.36
XBP1 P17861 1/20 0.36
PTBP1 P26599 1/20 0.36
HTT P42858 1/20 0.36
RAB9A P51151 1/20 0.36
GALK1 P51570 1/20 0.36
BLM P54132 1/20 0.36
SMAD3 P84022 1/20 0.36
KMT2A Q03164 1/20 0.36
ATM Q13315 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12367183 0.86 ALDH1A1 (0.38) PTPRCPTPN1L3MBTL1MAPTSMN1; SMN2
SCHEMBL13492554 0.81 ENPP1 (0.37) MAPTENPP1CYP1A2CYP3A4CYP2C9
SCHEMBL18905752 0.80 ENPP1 (0.44) L3MBTL1HTTNPSR1CRHBPCRHR2
SCHEMBL4074903 0.80 THRB (0.34) L3MBTL1MAPTSMN1; SMN2MEN1APAF1
SCHEMBL14226899 0.80 ENPP1 (0.44) L3MBTL1HTTNPSR1CRHBPCRHR2
SCHEMBL12202399 0.80 ACVR1 (0.40) L3MBTL1MAPTSMN1; SMN2MEN1APAF1
SCHEMBL12202393 0.80 ACVR1 (0.40) L3MBTL1MAPTSMN1; SMN2MEN1APAF1
SCHEMBL12367178 0.80 PDK2 (0.36) L3MBTL1MAPTSMN1; SMN2MEN1APAF1
SCHEMBL12726402 0.79 PTPRC (0.49) PTPRCPTPN1L3MBTL1MAPTSMN1; SMN2
SCHEMBL4076119 0.79 ENPP1 (0.42) L3MBTL1CRHBPCRHR2KEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110198582-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2011-08-18 US disclosed
US-20110198582-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2011-08-18 US disclosed
WO-2010047403-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2010-04-29 WO disclosed