SCHEMBL4074903

SCHEMBL4074903

c1ccc(-c2c3c(c(-c4ccccc4)c4ccccc24)-c2ccc(-c4ccc5c(-c6ccccc6)c6ccccc6c(-c6ccccc6)c5c4)c4cccc-3c24)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.34
MCL1 Q07820 1/20 0.34
ACMSD Q8TDX5 1/20 0.34
ENPP1 P22413 1/20 0.34
THRA P10827 1/20 0.34
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
ESR1 P03372 3/20 0.33
ESR2 Q92731 3/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
ACHE P22303 2/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33
HIF1A Q16665 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14330173 0.89 GABRA1 (0.35) L3MBTL1ALDH1A1HPGDTSHRMAPK1
SCHEMBL14330174 0.89 GABRA1 (0.35) L3MBTL1ALDH1A1HPGDTSHRMAPK1
SCHEMBL13957003 0.89 THRA (0.30) THRBMCL1ACMSDENPP1THRA
SCHEMBL21643677 0.88 MCL1 (0.39) MCL1ESR2ALDH1A1HPGDTSHR
SCHEMBL30169973 0.88 MCL1 (0.39) MCL1ESR2ALDH1A1HPGDTSHR
SCHEMBL21671249 0.87 MCL1 (0.36) MCL1ESR2ALDH1A1HPGDTSHR
SCHEMBL4076119 0.86 ENPP1 (0.42) ENPP1CRHBPCRHR2KEAP1NFE2L2
SCHEMBL14478592 0.86 MAPK1 (0.41) THRBENPP1ESR1ESR2L3MBTL1
SCHEMBL12269908 0.85 MEN1 (0.32) MEN1KMT2A
SCHEMBL12270038 0.85 DHODH (0.35) MCL1ACMSDENPP1L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11641776-B2 Organic compound, organic light emitting diode and organic light emitting device having the compound LG DISPLAY CO., LTD. (KR) 2023-05-02 US disclosed
EP-2085371-B1 FLUORANTHENE COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE USING THE FLUORANTHENE COMPOUND, AND ORGANIC ELECTROLUMINESCENT MATERIAL-CONTAINING SOLUTION IDEMITSU KOSAN CO (JP) 2015-10-07 EP disclosed
US-9120748-B2 Fluoranthene compound, organic electroluminescence device using the same, and solution containing organic electroluminescence material IDEMITSU KOSAN CO., LTD. (JP) 2015-09-01 US disclosed
EP-2085371-A1 FLUORANTHENE COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE USING THE FLUORANTHENE COMPOUND, AND ORGANIC ELECTROLUMINESCENT MATERIAL-CONTAINING SOLUTION Idemitsu Kosan Co., Ltd. (JP) 2009-08-05 EP disclosed
US-20090015144-A1 FLUORANTHENE COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME, AND SOLUTION CONTAINING ORGANIC ELECTROLUMINESCENCE MATERIAL IDEMITSU KOSAN CO., LTD. (JP) 2009-01-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090015144-A1 FLUORANTHENE COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME, AND SOLUTION CONTAINING ORGANIC ELECTROLUMINESCENCE MATERIAL LEF1, ESD, AFF2 THRB 4717/4885MCL1 2838/4885ACMSD 606/4885
US-11641776-B2 Organic compound, organic light emitting diode and organic light emitting device having the compound CYBA, CYP2C9, CYP3A4 THRB 3524/4885MCL1 2537/4885ACMSD 1825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.