Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13492121 | 0.86 | GAA (0.48) | CYP4Z1HSP90AB1SMN1; SMN2NLRP3GAA | |
| SCHEMBL4804283 | 0.84 | SMN1; SMN2 (0.42) | CYP4Z1HSP90AB1SMN1; SMN2NLRP3GAA | |
| SCHEMBL2926152 | 0.82 | HSP90AB1 (0.66) | ESR1HSP90AB1SMN1; SMN2HMGB1CXCL12 | |
| SCHEMBL9202564 | 0.82 | HSP90AB1 (0.66) | CYP4Z1ESR1HSP90AB1SMN1; SMN2GAA | |
| SCHEMBL7346341 | 0.81 | PTP4A1 (0.49) | CYP4Z1ESR1HSP90AB1SMN1; SMN2GAA | |
| SCHEMBL889921 | 0.81 | CYP4F2 (0.57) | CYP4Z1ESR1NLRP3GAAALDH1A1 | |
| SCHEMBL3649411 | 0.80 | ESR1 (0.53) | CYP4Z1ESR1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL2384365 | 0.80 | SMN1; SMN2 (0.46) | CYP4Z1HSP90AB1SMN1; SMN2NLRP3GAA | |
| SCHEMBL28673281 | 0.80 | SMN1; SMN2 (0.46) | CYP4Z1HSP90AB1SMN1; SMN2NLRP3GAA | |
| SCHEMBL6080931 | 0.80 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9982210-B2 | Composition containing heterocyclic compounds and a method of lubricating an internal combustion engine | THE LUBRIZOL CORPORATION (US) | 2018-05-29 | — | — | US | disclosed |
| US-8785357-B2 | Composition containing heterocyclic compounds and a method of lubricating an internal combustion engine | THE LUBRIZOL CORPORATION (US) | 2014-07-22 | — | — | US | disclosed |
| US-20140018268-A1 | Composition Containing Heterocyclic Compounds and a Method of Lubricating an Internal Combustion Engine | LUBRIZOL CORP (US) | 2014-01-16 | — | — | US | disclosed |
| CN-101102989-B | Substituted cyclopentanes or cyclopentanones for the treatment of ocular hypertension | ALLERGAN INC | 2011-11-16 | — | — | CN | disclosed |
| US-20110190180-A1 | Composition Containing Heterocyclic Compounds and a Method of Lubricating an Internal Combustion Engine | THE LUBRIZOL CORPORATION (US) | 2011-08-04 | — | — | US | disclosed |
| CN-101102989-A | Substituted cyclopentanes or cyclopentanones for the treatment of ocular hypertension | ALLERGAN INC (US) | 2008-01-09 | — | — | CN | disclosed |