SCHEMBL6080931

SCHEMBL6080931

Cc1cc(CC(=O)OCc2ccccc2)cc(C)c1O

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.67
MAPK1 P28482 1/20 0.67
L3MBTL1 Q9Y468 1/20 0.67
PAM P19021 1/20 0.51
ALOX5 P09917 1/20 0.51
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
ENPP2 Q13822 1/20 0.46
KMT2A Q03164 2/20 0.46
LMNA P02545 3/20 0.45
TDP1 Q9NUW8 2/20 0.45
SLC6A2 P23975 1/20 0.45
SLC6A3 Q01959 1/20 0.45
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19917497 0.83 ALDH1A1 (0.53) ALDH1A1MAPK1L3MBTL1ALOX5NPC1
SCHEMBL27499661 0.81 ALDH1A1 (0.92) ALDH1A1MAPK1L3MBTL1PAMENPP2
SCHEMBL361779 0.81 ALDH1A1 (1.00) ALDH1A1MAPK1L3MBTL1PAMENPP2
SCHEMBL12368043 0.80 CYP4Z1 (0.46) ALDH1A1ALOX5SMN1; SMN2
SCHEMBL11791534 0.80 ALDH1A1 (0.47) ALDH1A1MAPK1L3MBTL1NPC1RAB9A
SCHEMBL6784181 0.79 ALDH1A1 (0.96) ALDH1A1MAPK1L3MBTL1PAMENPP2
SCHEMBL3042119 0.79 TDP1 (0.64) ALDH1A1L3MBTL1NPC1RAB9ASMN1; SMN2
SCHEMBL21012091 0.79 ALDH1A1 (0.69) ALDH1A1MAPK1L3MBTL1PAMNPC1
SCHEMBL5793165 0.79 ALDH1A1 (0.55) ALDH1A1MAPK1L3MBTL1PAMSMN1; SMN2
SCHEMBL29169367 0.79 L3MBTL1 (0.79) ALDH1A1MAPK1L3MBTL1PAMNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060079696-A1 Substituted compounds derived from N-(benzyl)phenylacetamide, preparation and uses GENFIT (FR) 2006-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060079696-A1 Substituted compounds derived from N-(benzyl)phenylacetamide, preparation and uses AADAC, NAT1, PARN ALDH1A1 845/4885MAPK1 3624/4885L3MBTL1 2320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.