Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3655417 | 0.89 | THRB (0.45) | PTP4A1THRBESR1MAPTGAA | |
| SCHEMBL12428008 | 0.88 | ALOX5 (0.52) | MAPTGAAALOX15TSHRHSD17B10 | |
| SCHEMBL11147975 | 0.84 | THRB (0.46) | THRBMAPTGAACYP4Z1SMN1; SMN2 | |
| SCHEMBL16049214 | 0.83 | CYP4F2 (0.54) | PTP4A1THRBESR1MAPTGAA | |
| SCHEMBL24843182 | 0.81 | SMN1; SMN2 (0.44) | THRBMAPTGAAPKMCYP4Z1 | |
| SCHEMBL2786552 | 0.81 | HSP90AB1 (0.63) | THRBESR1MAPTGAAHSP90AB1 | |
| SCHEMBL12368043 | 0.81 | CYP4Z1 (0.46) | ESR1MAPTGAACYP4Z1HSP90AB1 | |
| SCHEMBL135908 | 0.81 | HDAC1 (0.51) | ESR1GAAPKMCYP4Z1SMN1; SMN2 | |
| SCHEMBL9202564 | 0.79 | HSP90AB1 (0.66) | ESR1MAPTGAACYP4Z1HSP90AB1 | |
| SCHEMBL12900615 | 0.79 | CYP4Z1 (0.46) | THRBMAPTPKMCYP4Z1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5284971-A | No cardiac side effects | SYNTEX (U.S.A.) INC. (US) | 1994-02-08 | — | — | US | disclosed |