Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1356676 | 0.87 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL28394133 | 0.84 | PKM (0.40) | ALDH1A1KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL21808035 | 0.84 | HTT (0.38) | ALDH1A1KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL6036448 | 0.84 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL17339179 | 0.84 | HTT (0.38) | ALDH1A1KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL28738082 | 0.84 | HTT (0.38) | ALDH1A1KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL28366695 | 0.84 | TDP1 (0.51) | ALDH1A1KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL9653355 | 0.84 | MAPT (0.40) | ALDH1A1KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL28401883 | 0.82 | KDM4E (0.39) | ALDH1A1KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL2335862 | 0.82 | MAPT (0.37) | ALDH1A1MAPTCYP3A4HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 509 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116179554-A | Conditional protein targeted degradation chimeric based on nucleic acid aptamer, and preparation method and application thereof | 山东师范大学 | 2023-05-30 | — | — | CN | claimed |
| US-20220404349-A1 | METHODS AND USES FOR REMOTELY TRIGGERED PROTEASE ACTIVITY MEASUREMENTS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-12-22 | — | — | US | claimed |
| EP-3310787-B9 | TAGGABLE HETEROAROMATIC DRUGS AND CONJUGATES THEREOF | UNIV RAMOT (IL) | 2020-07-01 | — | — | EP | claimed |
| EP-3310787-B1 | TAGGABLE HETEROAROMATIC DRUGS AND CONJUGATES THEREOF | UNIV RAMOT (IL) | 2020-01-29 | — | — | EP | claimed |
| US-20190144917-A1 | METHODS AND USES FOR REMOTELY TRIGGERED PROTEASE ACTIVITY MEASUREMENTS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-05-16 | — | — | US | claimed |
| EP-3452407-A1 | METHODS AND USES FOR REMOTELY TRIGGERED PROTEASE ACTIVITY MEASUREMENTS | Massachusetts Institute Of Technology (US) | 2019-03-13 | — | — | EP | claimed |
| WO-2017193070-A1 | METHODS AND USES FOR REMOTELY TRIGGERED PROTEASE ACTIVITY MEASUREMENTS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-11-09 | — | — | WO | claimed |
| CN-107002293-A | Pass through synthesis order-checking using pulse reading optical | 艾比斯生物科学公司 | 2017-08-01 | — | — | CN | claimed |
| WO-2015107071-A1 | GENETICALLY ENCODED SPIN LABEL | Universität Konstanz (DE) | 2015-07-23 | — | — | WO | claimed |
| CN-101591230-B | 2,4-dyhydroxyl chalcone derivative, preparation method and application thereof | TIANJIN INST PHARM RESEARCH | 2013-10-30 | — | — | CN | claimed |
| EP-1492798-A1 | N-(3-RIFAMYCINYL)-CARBAMATES, METHOD OF PREPARING THEM AND THEIR USE FOR TREATING AND PREVENTING TUBERCULOSIS | UNIVERSITY OF LEICESTER (GB) | 2005-01-05 | — | — | EP | claimed |
| WO-2003084965-A1 | N-(3-RIFAMYCINYL)-CARBAMATES, METHOD OF PREPARING THEM AND THEIR USE FOR TREATING AND PREVENTING TUBERCULOSIS | UFZ-UMWELTFORSCHUNGSZENTRUM LEIPZIG-HALLE GMBH (DE) | 2003-10-16 | — | — | WO | claimed |
| EP-1140880-A1 | HOMOPIPERAZINE DERIVATIVES AS SELECTIVE EMOPAMIL INHIBITORS | AstraZeneca AB (SE) | 2001-10-10 | — | — | EP | claimed |
| EP-0562025-B1 | Compounds and their use in a binary synthesis strategy | AFFYMETRIX INC (US) | 2001-02-07 | — | — | EP | claimed |
| WO-2000039110-A1 | HOMOPIPERAZINE DERIVATIVES AS SELECTIVE EMOPAMIL INHIBITORS | ASTRAZENECA AB (SE) | 2000-07-06 | — | — | WO | claimed |
| US-5451683-A | Spatially-addressable immobilization of anti-ligands on surfaces | AFFYMAX TECHNOLOGIES N.V. | 1995-09-19 | — | — | US | claimed |
| US-5231105-A | Ethylamine derivatives and antihypertensives containing the same | AJINOMOTO CO., INC. (JP) | 1993-07-27 | — | — | US | claimed |
| EP-0502060-A4 | SPATIALLY-ADDRESSABLE IMMOBILIZATION OF ANTI-LIGANDS ON SURFACES | — | 1993-05-05 | — | — | EP | claimed |
| EP-0502060-A1 | SPATIALLY-ADDRESSABLE IMMOBILIZATION OF ANTI-LIGANDS ON SURFACES | AFFYMAX TECHNOLOGIES N.V. (AN) | 1992-09-09 | — | — | EP | claimed |
| WO-1991007087-A1 | SPATIALLY-ADDRESSABLE IMMOBILIZATION OF ANTI-LIGANDS ON SURFACES | AFFYMAX TECHNOLOGIES N.V. (AN) | 1991-05-30 | — | — | WO | claimed |