Bupranolol

Bupranolol

SCHEMBL123717

Cc1ccc(Cl)c(OC[C@@H](O)CNC(C)(C)C)c1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.63
MEN1 O00255 1/20 0.63
HTT P42858 1/20 0.63
KMT2A Q03164 1/20 0.63
NPSR1 Q6W5P4 2/20 0.56
ACHE P22303 1/20 0.56
MAPT P10636 2/20 0.56
GLA P06280 1/20 0.56
SLC2A1 P11166 1/20 0.54
CYP2D6 P10635 2/20 0.52
ADRB2 P07550 3/20 0.52
ADRB1 P08588 2/20 0.52
HTR1A P08908 1/20 0.51
ADRA2A P08913 1/20 0.51
ADRA2B P18089 1/20 0.51
MAOA P21397 1/20 0.51
HTR2B P41595 1/20 0.51
ADRB3 P13945 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bupranolol SCHEMBL29518497 1.00 L3MBTL1 (0.63) L3MBTL1MEN1HTTKMT2ANPSR1
Bupranolol SCHEMBL34061 1.00 L3MBTL1 (0.63) L3MBTL1MEN1HTTKMT2ANPSR1
Bupranolol SCHEMBL2497819 1.00 L3MBTL1 (0.63) L3MBTL1MEN1HTTKMT2ANPSR1
Bupranolol SCHEMBL6508337 1.00 L3MBTL1 (0.63) L3MBTL1MEN1HTTKMT2ANPSR1
Bupranolol SCHEMBL348360 0.99 L3MBTL1 (0.65) L3MBTL1MEN1HTTKMT2ANPSR1
Bupranolol SCHEMBL348362 0.99 L3MBTL1 (0.65) L3MBTL1MEN1HTTKMT2ANPSR1
SCHEMBL348361 0.92 L3MBTL1 (0.63) L3MBTL1MEN1HTTKMT2ANPSR1
Bupranolol SCHEMBL8908385 0.90 L3MBTL1 (0.53) L3MBTL1MEN1HTTKMT2ANPSR1
Bupranolol SCHEMBL19816741 0.89 LMNA (0.55) L3MBTL1MEN1HTTKMT2ANPSR1
SCHEMBL12215557 0.88 SLC2A1 (0.57) L3MBTL1MEN1HTTKMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4722714-A1 SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) Korea Institute of Science and Technology (KR) 2026-04-08 EP claimed
US-20240301022-A1 GLYCOPROTEINS HAVING LIPID MOBILIZING PROPERTIES AND THERAPEUTIC USES THEREOF UNIV ASTON (GB) 2024-09-12 US claimed
EP-3485908-B1 THERAPEUTIC COMBINATION AND USE OF DLL4 ANTAGONIST ANTIBODIES AND ANTI-HYPERTENSIVE AGENTS MEREO BIOPHARMA 5 INC (US) 2021-08-18 EP claimed
EP-3072526-B1 THERAPEUTIC COMBINATION AND USE OF DLL4 ANTAGONIST ANTIBODIES AND ANTI-HYPERTENSIVE AGENTS ONCOMED PHARM INC (US) 2018-09-26 EP claimed
EP-3072978-B1 1L1RL-1 AS A CARDIOVASCULAR DISEASE MARKER BRIGHAM & WOMENS HOSPITAL INC (US) 2018-07-11 EP claimed
CN-107753471-A A kind of pharmaceutical composition for treating obesity-related hypertension patient and preparation method thereof 郭裴哲 2018-03-06 CN claimed
EP-2336359-B1 1L1RL-1 as a cardiovascular disease marker BRIGHAM & WOMENS HOSPITAL (US) 2016-04-20 EP claimed
EP-2488204-B1 THERAPEUTIC COMBINATION AND USE OF DLL4 ANTAGONIST ANTIBODIES AND ANTI-HYPERTENSIVE AGENTS ONCOMED PHARM INC (US) 2016-04-06 EP claimed
EP-2268612-B1 ARYLSULFONAMIDE-BASED MATRIX METALLOPROTEASE INHIBITORS NOVARTIS AG (CH) 2014-08-20 EP claimed
EP-2586401-B1 Implantable film/mesh composite COVIDIEN LP (US) 2014-03-19 EP claimed
EP-0229947-B1 NOVEL CRYSTALLINE SALTS OF ARYLOXY-PROPANOLAMINES, THEIR PREPARATION AND THEIR USE RORER INTERNATIONAL (OVERSEAS) INC. (US) 1991-03-13 EP claimed
EP-0384266-A2 Therapeutic system for the sustained and controlled transdermal or transmucosal delivery of active agents LTS Lohmann Therapie-Systeme GmbH & Co. KG (DE) 1990-08-29 EP claimed
EP-0384267-A2 Therapeutic system for the sustained and controlled transdermal or transmucosal delivery of active agents LTS Lohmann Therapie-Systeme GmbH & Co. KG (DE) 1990-08-29 EP claimed
EP-0036138-B2 Composition of matter for topical application comprising a bio-affecting agent and N,N-diethyl-m-toluamide MERCK & CO. INC. (US) 1989-10-25 EP claimed
EP-0069385-B1 USE OF EUCALYPTOL FOR ENHANCING SKIN PERMEATION OF BIOAFFECTING AGENTS MERCK & CO. INC. (US) 1987-10-14 EP claimed
EP-0229947-A1 Novel crystalline salts of aryloxy-propanolamines, their preparation and their use RORER INTERNATIONAL (OVERSEAS) INC. (US) 1987-07-29 EP claimed
EP-0073819-B1 NASAL ADMINISTRATION OF BETA-BLOCKERS AND DOSAGE FORMS THEREFOR The University of Kentucky Research Foundation (US) 1987-05-27 EP claimed
EP-0186019-A2 Medicated dressing SCHWARZ PHARMA AG (DE) 1986-07-02 EP claimed
EP-0036138-B1 COMPOSITION OF MATTER FOR TOPICAL APPLICATION COMPRISING A BIO-AFFECTING AGENT AND N,N-DIETHYL-M-TOLUAMIDE MERCK & CO. INC. (US) 1985-08-28 EP claimed
EP-0152379-A2 Process for preparing pharmaceutical compositions containing unilamellar liposomes CIBA-GEIGY AG (CH) 1985-08-21 EP claimed