Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bupranolol SCHEMBL29518497 | 0.90 | L3MBTL1 (0.63) | L3MBTL1MEN1KMT2AHTTCYP2D6 | |
| Bupranolol SCHEMBL2497819 | 0.90 | L3MBTL1 (0.63) | L3MBTL1MEN1KMT2AHTTCYP2D6 | |
| Bupranolol SCHEMBL123717 | 0.90 | L3MBTL1 (0.63) | L3MBTL1MEN1KMT2AHTTCYP2D6 | |
| Bupranolol SCHEMBL6508337 | 0.90 | L3MBTL1 (0.63) | L3MBTL1MEN1KMT2AHTTCYP2D6 | |
| Bupranolol SCHEMBL34061 | 0.90 | L3MBTL1 (0.63) | L3MBTL1MEN1KMT2AHTTCYP2D6 | |
| Bupranolol SCHEMBL348362 | 0.89 | L3MBTL1 (0.65) | L3MBTL1MEN1KMT2AHTTCYP2D6 | |
| Bupranolol SCHEMBL348360 | 0.89 | L3MBTL1 (0.65) | L3MBTL1MEN1KMT2AHTTCYP2D6 | |
| SCHEMBL348361 | 0.82 | L3MBTL1 (0.63) | L3MBTL1MEN1KMT2AHTTCYP2D6 | |
| Bupranolol SCHEMBL5485004 | 0.82 | L3MBTL1 (0.51) | L3MBTL1MEN1KMT2AHTTCYP2D6 | |
| Bupranolol SCHEMBL19816741 | 0.80 | LMNA (0.55) | L3MBTL1MEN1KMT2AHTTADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5603948-A | MIXING COMPONENTS OF HOT-MELT ADHESIVE UNDER HEATING IN INERT GAS ATMOSPHERE UNTIL HOMOGENEOUS MELT IS OBTAINED, DISSOLVING ACTIVE INGREDIENT THEREIN, APPLYING TO IMPERMEABLE COVER LAYER | SCHWARZ PHARMA AG (DE) | 1997-02-18 | — | — | US | disclosed |