Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264858 | 1.00 | GLS (0.38) | GLSGLANPSR1 | |
| SCHEMBL21726164 | 1.00 | GLS (0.38) | GLSGLANPSR1 | |
| SCHEMBL21726166 | 0.80 | GLS (0.40) | GLSGLANPSR1 | |
| SCHEMBL9196022 | 0.80 | GLS (0.40) | GLSGLANPSR1 | |
| SCHEMBL21726165 | 0.80 | GLS (0.40) | GLSGLANPSR1 | |
| SCHEMBL11986915 | 0.78 | GLS (0.37) | GLSGLANPSR1 | |
| SCHEMBL1740025 | 0.78 | GLS (0.40) | GLSGLANPSR1 | |
| SCHEMBL2158180 | 0.78 | GLS (0.40) | GLSGLANPSR1 | |
| SCHEMBL11986916 | 0.78 | GLS (0.40) | GLSGLANPSR1 | |
| SCHEMBL8775455 | 0.78 | PTPN1 (0.44) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9256125-B2 | Acid generators and photoresists comprising same | ROHM AND HAAS ELECTRONIC MATERIALS, LLC (US) | 2016-02-09 | — | — | US | disclosed |
| US-9174969-B2 | Indoline scaffold SHP-2 inhibitors and cancer treatment method | UNIVERSITY OF SOUTH FLORIDA (US) | 2015-11-03 | — | — | US | disclosed |
| US-20140295347-A1 | ACID GENERATORS AND PHOTORESISTS COMPRISING SAME | ROHM AND HAAS ELECTRONIC MATERIALS, LLC (US) | 2014-10-02 | — | — | US | disclosed |
| US-7994331-B2 | Heterocycle-substituted benzimidazole derivative | MSD K.K. (JP) | 2011-08-09 | — | — | US | disclosed |
| US-7994331-B2 | Heterocycle-substituted benzimidazole derivative | MSD K.K. (JP) | 2011-08-09 | — | — | US | disclosed |
| US-20110190315-A1 | INDOLINE SCAFFOLD SHP-2 INHIBITORS AND CANCER TREATMENT METHOD | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-08-04 | — | — | US | disclosed |
| US-20110190315-A1 | INDOLINE SCAFFOLD SHP-2 INHIBITORS AND CANCER TREATMENT METHOD | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-08-04 | — | — | US | disclosed |
| US-20100087360-A1 | Heterocycle-substituted benzimidazole derivative | MSD K.K. (JP) | 2010-04-08 | — | — | US | disclosed |
| US-20100087360-A1 | Heterocycle-substituted benzimidazole derivative | MSD K.K. (JP) | 2010-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140295347-A1 | ACID GENERATORS AND PHOTORESISTS COMPRISING SAME | PPOX, HAO2, DUOX1 | GLS 2166/4885GLA 1476/4885NPSR1 1924/4885 |
| US-20100087360-A1 | Heterocycle-substituted benzimidazole derivative | GCK, GCKR, HK1 | GLS 20/4885GLA 1035/4885NPSR1 3924/4885 |
| US-20110190315-A1 | INDOLINE SCAFFOLD SHP-2 INHIBITORS AND CANCER TREATMENT METHOD | PTPN7, PTPN3, PTPN5 | GLS 4067/4885GLA 4770/4885NPSR1 512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.