SCHEMBL12372710

SCHEMBL12372710

C=C(C)C(=O)OCCOc1ccc(/C=C(\C#N)C(=O)OC)cc1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.53
KDM4E B2RXH2 7/20 0.53
MAPT P10636 4/20 0.53
KMT2A Q03164 3/20 0.53
TDP1 Q9NUW8 3/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
DNM1 Q05193 2/20 0.48
MEN1 O00255 2/20 0.47
LMNA P02545 2/20 0.47
POLB P06746 1/20 0.45
APEX1 P27695 1/20 0.45
HTT P42858 1/20 0.45
HPGD P15428 4/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
GAA P10253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10694794 0.89 KDM4E (0.59) ALDH1A1KDM4EMAPTKMT2ATDP1
SCHEMBL10694789 0.89 KDM4E (0.59) ALDH1A1KDM4EMAPTKMT2ATDP1
SCHEMBL15491125 0.85 DNM1 (0.55) ALDH1A1KDM4EMAPTKMT2ATDP1
SCHEMBL8748455 0.85 APEX1 (0.49) ALDH1A1KDM4EMAPTKMT2ATDP1
SCHEMBL10694876 0.85 ALDH1A1 (0.58) ALDH1A1KDM4EMAPTKMT2ATDP1
SCHEMBL13919933 0.84 ALDH1A1 (0.59) ALDH1A1KDM4EMAPTKMT2ATDP1
SCHEMBL9680658 0.83 POLB (0.59) ALDH1A1KDM4ETDP1DNM1POLB
SCHEMBL12477636 0.83 ALDH1A1 (0.56) ALDH1A1KDM4EMAPTKMT2ATDP1
SCHEMBL141604 0.83 ALDH1A1 (0.56) ALDH1A1KDM4EMAPTKMT2ATDP1
SCHEMBL12372703 0.83 KDM4E (0.56) ALDH1A1KDM4EMAPTKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7989572-B2 Polyvinyl ultraviolet light absorbers for personal care EASTMAN CHEMICAL COMPANY (US) 2011-08-02 US disclosed
WO-2009091506-A2 POLYVINYL ULTRAVIOLET LIGHT ABSORBERS FOR PERSONAL CARE EASTMAN CHEMICAL COMPANY (US) 2009-07-23 WO disclosed
US-20090185988-A1 POLYVINYL ULTRAVIOLET LIGHT ABSORBERS FOR PERSONAL CARE EASTMAN CHEMICAL COMPANY (US) 2009-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090185988-A1 POLYVINYL ULTRAVIOLET LIGHT ABSORBERS FOR PERSONAL CARE MMS19, XPA, CUTA ALDH1A1 1754/4885KDM4E 3348/4885MAPT 588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.