Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10029848 | 1.00 | LTA4H (0.53) | LTA4HCYP17A1CYP11B1CYP11B2KCNH2 | |
| SCHEMBL15591130 | 1.00 | LTA4H (0.53) | LTA4HCYP17A1CYP11B1CYP11B2KCNH2 | |
| SCHEMBL8014120 | 0.98 | LTA4H (0.55) | LTA4HCYP17A1CYP11B1CYP11B2KCNH2 | |
| SCHEMBL2344484 | 0.98 | LTA4H (0.55) | LTA4HCYP17A1CYP11B1CYP11B2KCNH2 | |
| SCHEMBL15591131 | 0.94 | LTA4H (0.48) | LTA4HCYP17A1CYP11B1CYP11B2KCNH2 | |
| SCHEMBL867469 | 0.92 | LTA4H (0.50) | LTA4HCYP17A1CYP11B1CYP11B2KCNH2 | |
| SCHEMBL14253104 | 0.92 | LTA4H (0.50) | LTA4HCYP17A1CYP11B1CYP11B2KCNH2 | |
| SCHEMBL12372897 | 0.88 | APP (0.51) | LTA4HCYP17A1CYP11B1CYP11B2KCNH2 | |
| SCHEMBL12893274 | 0.88 | LTA4H (0.47) | LTA4HCYP17A1CYP11B1CYP11B2KCNH2 | |
| SCHEMBL7263726 | 0.88 | ALDH1A1 (0.50) | LTA4HCYP17A1CYP11B1CYP11B2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9112167-B2 | Aromatic amine derivatives and organic electroluminescent device using same | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 2015-08-18 | — | — | US | disclosed |
| US-9112167-B2 | Aromatic amine derivatives and organic electroluminescent device using same | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 2015-08-18 | — | — | US | disclosed |
| US-20140077200-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | SONY CORPORATION (JP) | 2014-03-20 | — | — | US | disclosed |
| US-20140077200-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | SONY CORPORATION (JP) | 2014-03-20 | — | — | US | disclosed |
| WO-2013168084-A1 | OPTOELECTRONIC COMPONENTS COMPRISING ORGANIC HOLE TRANSPORT MATERIAL | HELIATEK GMBH (DE) | 2013-11-14 | — | — | WO | disclosed |
| US-20080108832-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2008-05-08 | — | — | US | disclosed |
| US-20080108832-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108832-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | ALKBH3, EML4, ALKBH2 | LTA4H 1751/4885CYP17A1 3778/4885CYP11B1 4071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.