Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15828189 | 0.98 | KDM4E (0.31) | KDM4EMAPK1HIF1AACHE | |
| SCHEMBL15836830 | 0.94 | ACHE (0.38) | ACHE | |
| SCHEMBL18176168 | 0.94 | — | — | |
| SCHEMBL12094903 | 0.93 | KDM4E (0.34) | KDM4EMAPK1HIF1AACHE | |
| SCHEMBL15828198 | 0.92 | ACHE (0.37) | ACHE | |
| SCHEMBL16881930 | 0.92 | ACHE (0.37) | ACHE | |
| SCHEMBL443374 | 0.90 | KDM4E (0.32) | KDM4EMAPK1HIF1AACHE | |
| SCHEMBL26259471 | 0.88 | KDM4E (0.31) | KDM4EMAPK1HIF1AACHE | |
| SCHEMBL12222638 | 0.88 | KDM4E (0.38) | KDM4EMAPK1HIF1AACHE | |
| SCHEMBL26688049 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873361-B2 | Ophthalmic devices | BAUSCH + LOMB IRELAND LIMITED (IE) | 2024-01-16 | — | — | US | disclosed |
| US-11829008-B2 | Increased stiffness center optic in soft contact lenses for astigmatism correction | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-11754754-B2 | Silicone hydrogels comprising N-alkyl methacrylamides and contact lenses made thereof | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2023-09-12 | — | — | US | disclosed |
| US-20230244000-A1 | MULTIFUNCTIONAL CROSSLINKING AGENTS AND OPHTHALMIC DEVICES FORMED THEREFROM | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT | 2023-08-03 | — | — | US | disclosed |
| US-20180011223-A1 | SILICONE HYDROGELS COMPRISING N-ALKYL METHACRYLAMIDES AND CONTACT LENSES MADE THEREOF | JOHNSON & JOHNSON VISION CARE, INC. | 2018-01-11 | — | — | US | disclosed |
| US-20140179867-A1 | MONOMER MIXTURES FOR FORMING SILICON HYDROGELS | BAUSCH & LOMB INCORPORATED (US) | 2014-06-26 | — | — | US | disclosed |
| US-7994356-B2 | Mono ethylenically unsaturated polycarbosiloxane monomers | BAUSCH & LOMB INCORPORATED (US) | 2011-08-09 | — | — | US | disclosed |
| US-20110009587-A1 | MONO ETHYLENICALLY UNSATURATED POLYCARBOSILOXANE MONOMERS | ORAPHARMA, INC. | 2011-01-13 | — | — | US | disclosed |
| US-20110009658-A1 | Mono Ethylenically Unsaturated Polycarbosiloxane Monomers | BAUSCH HEALTH AMERICAS, INC. | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009658-A1 | Mono Ethylenically Unsaturated Polycarbosiloxane Monomers | ALOX5, ALOX12, ELOVL5 | KDM4E 2360/4885MAPK1 2909/4885HIF1A 159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.