Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12759308 | 0.98 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12759258 | 0.91 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12759261 | 0.91 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12373191 | 0.91 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12759322 | 0.91 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12759262 | 0.91 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12759260 | 0.91 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL35612 | 0.91 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL35511 | 0.91 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7127653 | 0.90 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994356-B2 | Mono ethylenically unsaturated polycarbosiloxane monomers | BAUSCH & LOMB INCORPORATED (US) | 2011-08-09 | — | — | US | disclosed |
| US-20110009658-A1 | Mono Ethylenically Unsaturated Polycarbosiloxane Monomers | BAUSCH HEALTH AMERICAS, INC. | 2011-01-13 | — | — | US | disclosed |
| US-20110009587-A1 | MONO ETHYLENICALLY UNSATURATED POLYCARBOSILOXANE MONOMERS | ORAPHARMA, INC. | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009658-A1 | Mono Ethylenically Unsaturated Polycarbosiloxane Monomers | ALOX5, ALOX12, ELOVL5 | TSHR 4814/4885THRB 4789/4885POLB 1922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.