SCHEMBL12374318

SCHEMBL12374318

Cc1ccc(N(CN(c2ccccc2)c2ccc(C)cc2)c2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.52
TSHR P16473 2/20 0.46
ACHE P22303 2/20 0.46
LMNA P02545 2/20 0.46
ALOX12 P18054 1/20 0.46
ALDH1A1 P00352 1/20 0.44
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
HPGD P15428 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
TRPM8 Q7Z2W7 1/20 0.38
NR3C2 P08235 1/20 0.38
HTT P42858 1/20 0.38
MEN1 O00255 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
KMT2A Q03164 1/20 0.38
CNR2 P34972 2/20 0.37
CNR1 P21554 1/20 0.37
TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14962874 1.00 CYP2C19 (0.52) CYP2C19TSHRACHELMNAALOX12
SCHEMBL14203430 0.88 CYP2C19 (0.43) CYP2C19TSHRACHELMNAALOX12
SCHEMBL1304312 0.84 KCNH2 (0.41) CYP2C19TSHRALDH1A1TDP1HTT
SCHEMBL5609630 0.84 NR3C2 (0.53) CYP2C19TSHRACHELMNAALOX12
SCHEMBL10153572 0.80 CYP2C19 (0.62) CYP2C19TSHRLMNAALDH1A1NR3C2
SCHEMBL9446198 0.80 CYP2C19 (0.68) CYP2C19TSHRLMNAALDH1A1NR3C2
SCHEMBL12763844 0.80 CYP2C19 (0.62) CYP2C19TSHRLMNAALDH1A1NR3C2
SCHEMBL21146865 0.80 NR3C2 (0.50) CYP2C19TSHRACHELMNAALOX12
SCHEMBL14258202 0.80 ALDH1A1 (0.54) CYP2C19TSHRALDH1A1TDP1NR3C2
SCHEMBL11697232 0.79 KDM4E (0.49) CYP2C19TSHRACHELMNAALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9331284-B2 Polymer compound and light-emitting device using same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-05-03 US disclosed
US-9269905-B2 Polymer compound having carbon cluster structure and organic device using same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-02-23 US disclosed
US-20130270545-A1 POLYMER COMPOUND HAVING CARBON CLUSTER STRUCTURE AND ORGANIC DEVICE USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-10-17 US disclosed
US-20120326140-A1 POLYMER COMPOUND AND LIGHT-EMITTING DEVICE USING SAME CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2012-12-27 US disclosed
US-20110187266-A1 POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-04 US disclosed
US-7651746-B2 Halogenated bisdiarylaminopolycyclic aromatic compounds and polymers thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-01-26 US disclosed
US-7351788-B2 Polymer containing substituted triphenylamine units CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2008-04-01 US disclosed
US-20070126345-A1 Halogenated bisdiarylaminopolycylic aromatic compounds and polymers thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120326140-A1 POLYMER COMPOUND AND LIGHT-EMITTING DEVICE USING SAME CCNA1, CCNB1, CCNL2 CYP2C19 634/4885TSHR 2469/4885ACHE 2098/4885
US-20070126345-A1 Halogenated bisdiarylaminopolycylic aromatic compounds and polymers thereof AHR, AADAC, ARNT CYP2C19 333/4885TSHR 2262/4885ACHE 4213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.