SCHEMBL12374432

SCHEMBL12374432

C=Cc1cc(C(c2cc(CC)c(N)c(CC)c2)c2c(Cl)cccc2Cl)cc(CC)c1N

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13636830 0.94 ALDH1A1 (0.32) ALDH1A1
SCHEMBL12374450 0.88 POLB (0.36) ALDH1A1CYP3A4CYP2D6SLC6A2SLC6A4
SCHEMBL14123442 0.77 PNMT (0.35) ALDH1A1CYP3A4CYP2D6SLC6A2SLC6A4
SCHEMBL14117907 0.76 PNMT (0.34) ALDH1A1CYP3A4CYP2D6SLC6A2SLC6A4
SCHEMBL12374434 0.72 ALDH1A1 (0.31) ALDH1A1
SCHEMBL5010062 0.72 GAA (0.40) CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3
SCHEMBL13069412 0.71 CYP1A2 (0.40) ALDH1A1CYP3A4CYP2D6
SCHEMBL10742146 0.67 GABRA1 (0.40) ALDH1A1
SCHEMBL5011788 0.66 HTT (0.40) ALDH1A1SLC6A2SLC6A4SLC6A3
SCHEMBL28252384 0.66 HTT (0.40) ALDH1A1SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8303671-B2 Mixture of basic dye and acid dye with wax XEROX CORPORATION (US) 2012-11-06 US disclosed
US-7997712-B2 Phase change inks containing colorant compounds XEROX CORPORATION (US) 2011-08-16 US disclosed
US-20080186371-A1 Phase change inks containing colorant compounds XEROX CORPORATION 2008-08-07 US disclosed
US-20080184911-A1 Colorant compounds XEROX CORPORATION 2008-08-07 US disclosed