Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TYR | P14679 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597386 | 0.82 | TRPA1 (0.46) | ALDH1A1ALOX15HSD17B10TRPA1TP53 | |
| SCHEMBL30135130 | 0.82 | TRPA1 (0.46) | ALDH1A1ALOX15HSD17B10TRPA1TP53 | |
| SCHEMBL30553420 | 0.81 | TRPA1 (0.45) | ALDH1A1ALOX15HSD17B10TRPA1TP53 | |
| SCHEMBL2787846 | 0.81 | TRPA1 (0.45) | ALDH1A1ALOX15HSD17B10TRPA1TP53 | |
| SCHEMBL5983335 | 0.81 | TAAR1 (0.45) | ALDH1A1ALOX15HSD17B10TDP1LMNA | |
| SCHEMBL11865746 | 0.79 | ALDH1A1 (0.61) | ALDH1A1ALOX15HSD17B10TRPA1TP53 | |
| SCHEMBL11317550 | 0.79 | CNR1 (0.48) | ALDH1A1ALOX15HSD17B10TRPA1TP53 | |
| SCHEMBL12374528 | 0.78 | ALDH1A1 (0.37) | ALDH1A1ALOX15HSD17B10TRPA1TP53 | |
| SCHEMBL28512543 | 0.78 | ALDH1A1 (0.59) | ALDH1A1ALOX15HSD17B10TRPA1TP53 | |
| SCHEMBL270433 | 0.77 | ALDH1A1 (0.64) | ALDH1A1ALOX15HSD17B10TRPA1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207956-A1 | INTRAMOLECULAR C-H AMINATION WITH PHOSPHORYL AZIDES | NATIONAL SCIENCE FOUNDATION | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207956-A1 | INTRAMOLECULAR C-H AMINATION WITH PHOSPHORYL AZIDES | CYCS, CCNH, CBR3 | ALDH1A1 3120/4885ALOX15 4157/4885HSD17B10 3091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.