Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.36 |
| ▸ | RECQL | P46063 | 3/20 | 0.36 |
| ▸ | APEX1 | P27695 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5175624 | 0.81 | ALDH1A1 (0.57) | ALDH1A1ALOX15LMNAHSD17B10CYP2C9 | |
| SCHEMBL5983335 | 0.78 | TAAR1 (0.45) | ALDH1A1ALOX15LMNAHSD17B10CYP2C9 | |
| SCHEMBL12374570 | 0.78 | ALDH1A1 (0.45) | ALDH1A1ALOX15LMNAHSD17B10CYP2C9 | |
| SCHEMBL12405380 | 0.74 | ALDH1A1 (0.51) | ALDH1A1ALOX15TYRKDM4EMAPT | |
| SCHEMBL81339 | 0.73 | KIF11 (0.49) | ALDH1A1HSD17B10KDM4EMAPTGAA | |
| SCHEMBL8418968 | 0.72 | ALOX15 (0.48) | ALDH1A1ALOX15LMNAHSD17B10CYP2C9 | |
| SCHEMBL10950826 | 0.72 | ALDH1A1 (0.55) | ALDH1A1ALOX15LMNAHSD17B10CYP2C9 | |
| SCHEMBL144360 | 0.71 | ALDH1A1 (0.58) | ALDH1A1ALOX15LMNAHSD17B10CYP2C9 | |
| SCHEMBL12374527 | 0.70 | TTR (0.33) | ALDH1A1MAPTGAAPOLBGFER | |
| SCHEMBL9489396 | 0.70 | ESR1 (0.48) | ALDH1A1ALOX15LMNAHSD17B10CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207956-A1 | INTRAMOLECULAR C-H AMINATION WITH PHOSPHORYL AZIDES | NATIONAL SCIENCE FOUNDATION | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207956-A1 | INTRAMOLECULAR C-H AMINATION WITH PHOSPHORYL AZIDES | CYCS, CCNH, CBR3 | ALDH1A1 3120/4885ALOX15 4157/4885LMNA 4341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.