SCHEMBL12374625

SCHEMBL12374625

CC1C(C)N1C1OC(CO)C(O)C1O

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CDK1 P06493 1/20 0.42
▸ CDA P32320 7/20 0.41
▸ MAPT P10636 1/20 0.41
▸ LGALS1 P09382 2/20 0.41
▸ LGALS3 P17931 2/20 0.41
▸ LGALS9 O00182 1/20 0.41
▸ LGALS8 O00214 1/20 0.41
▸ SLC28A1 O00337 1/20 0.41
▸ SLC28A2 O43868 1/20 0.41
▸ SLC29A1 Q99808 1/20 0.41
▸ SLC28A3 Q9HAS3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19317500 0.71 LGALS1 (0.59) LGALS1LGALS3LGALS9LGALS8
SCHEMBL15314105 0.71 LGALS1 (0.59) LGALS1LGALS3LGALS9LGALS8
SCHEMBL5452516 0.71 LGALS1 (0.59) LGALS1LGALS3LGALS9LGALS8
SCHEMBL24115372 0.71 LGALS1 (0.59) LGALS1LGALS3LGALS9LGALS8
SCHEMBL5452134 0.71 LGALS1 (0.59) LGALS1LGALS3LGALS9LGALS8
SCHEMBL24243426 0.71 LGALS1 (0.59) LGALS1LGALS3LGALS9LGALS8
SCHEMBL13632537 0.71 LGALS1 (0.59) LGALS1LGALS3LGALS9LGALS8
SCHEMBL13197776 0.71 LGALS1 (0.59) LGALS1LGALS3LGALS9LGALS8
SCHEMBL4439225 0.71 LGALS1 (0.59) LGALS1LGALS3LGALS9LGALS8
SCHEMBL17931796 0.71 LGALS1 (0.59) LGALS1LGALS3LGALS9LGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8003769-B2 Dye-labeled ribonucleotide triphosphates APPLIED BIOSYSTEMS, LLC (US) 2011-08-23 — — US disclosed
US-20100292457-A1 Dye-labeled ribonucleotide triphosphates APPLIED BIOSYSTEMS, LLC (US) 2010-11-18 — — US disclosed
US-7678892-B2 Dye-labeled ribonucleotide triphosphates APPLIED BIOSYSTEMS, LLC (US) 2010-03-16 — — US disclosed
US-20070293662-A1 Dye-labeled ribonucleotide triphosphates APPLERA CORPORATION (US) 2007-12-20 — — US disclosed
US-7262029-B2 Dye-labeled ribonucleotide triphosphates APPLERA CORPORATION (US) 2007-08-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100292457-A1 Dye-labeled ribonucleotide triphosphates DUT, POLRMT, SAMHD1 CDK1 2394/4885CDA 183/4885MAPT 3687/4885
US-20070293662-A1 Dye-labeled ribonucleotide triphosphates DUT, POLRMT, SAMHD1 CDK1 2394/4885CDA 183/4885MAPT 3687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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