Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.74 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.60 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7153117 | 0.90 | MAPT (0.64) | LMNAMAPTKMT2AMEN1AKR1C3 | |
| SCHEMBL30441386 | 0.90 | MAPT (0.64) | LMNAMAPTKMT2AMEN1AKR1C3 | |
| SCHEMBL23675133 | 0.88 | MAPT (0.81) | LMNAMAPTKMT2AMEN1AKR1C3 | |
| SCHEMBL145023 | 0.88 | MAPT (0.62) | LMNAMAPTKMT2AMEN1AKR1C3 | |
| SCHEMBL12089421 | 0.88 | HCAR3 (0.75) | LMNAMAPTKMT2AMEN1AKR1C3 | |
| SCHEMBL26931842 | 0.86 | KMT2A (0.80) | LMNAMAPTKMT2AMEN1AKR1C3 | |
| SCHEMBL15021452 | 0.86 | MAPT (0.63) | LMNAMAPTKMT2AMEN1AKR1C3 | |
| SCHEMBL25250478 | 0.85 | MAPT (0.59) | LMNAMAPTKMT2AMEN1AKR1C3 | |
| SCHEMBL2277928 | 0.84 | MAPT (0.64) | LMNAMAPTKMT2AMEN1AKR1C3 | |
| SCHEMBL7153363 | 0.82 | MAPT (0.58) | LMNAMAPTKMT2AMEN1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023236820-A1 | AROMATIC SIX-MEMBERED RING-FUSED IMIDAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 沈阳药科大学 | 2023-12-14 | — | — | WO | disclosed |
| CN-116120239-A | Aromatic six-membered cycloimidazole derivative, and preparation method and application thereof | 沈阳药科大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-114853680-A | Aromatic six-membered ring imidazole derivative and preparation method and application thereof | 沈阳药科大学 | 2022-08-05 | — | — | CN | disclosed |
| US-8470819-B2 | Benzimidazole and aza-benzimidazole carboxamides | MERCK SHARP & DOHME CORP. (US) | 2013-06-25 | — | — | US | disclosed |
| US-20110207750-A1 | BENZIMIDAZOLE AND AZA-BENZIMIDAZOLE CARBOXAMIDES | MERCK SHARP & DOHME LLC | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207750-A1 | BENZIMIDAZOLE AND AZA-BENZIMIDAZOLE CARBOXAMIDES | PAFAH1B3, PAFAH1B2, PAF1 | LMNA 1869/4885MAPT 4800/4885KMT2A 841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.