Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.33 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | FURIN | P09958 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16590761 | 0.89 | NFE2L2 (0.39) | PTGS2SLC9A1SLC9A3SLC9A2PTGS1 | |
| SCHEMBL21881 | 0.81 | TDP1 (0.67) | TP53TDP1ALDH1A1TSHRPTGS2 | |
| SCHEMBL5854212 | 0.80 | TP53 (0.56) | TP53TDP1ALDH1A1TSHRPTGS2 | |
| SCHEMBL2283814 | 0.78 | UNG (0.48) | ALDH1A1PTGS2SLC9A1SLC9A3SLC9A2 | |
| Ammonia Solution, Strong SCHEMBL31335086 | 0.78 | TDP1 (0.64) | TP53TDP1ALDH1A1TSHRPTGS2 | |
| SCHEMBL30381592 | 0.78 | TDP1 (0.64) | TP53TDP1ALDH1A1TSHRPTGS2 | |
| Water SCHEMBL20239051 | 0.78 | TDP1 (0.64) | TP53TDP1ALDH1A1TSHRPTGS2 | |
| SCHEMBL19056944 | 0.77 | TRIM24 (0.40) | PTGS1FBP1HDAC8NFE2L2MEN1 | |
| SCHEMBL12014958 | 0.77 | ALDH1A1 (0.58) | TP53TDP1ALDH1A1TSHRTRPA1 | |
| Hydrochloric Acid SCHEMBL29128956 | 0.76 | TDP1 (0.61) | TP53TDP1ALDH1A1TSHRPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9017907-B2 | Flexible imaging members having externally plasticized imaging layer(s) | XEROX CORPORATION (US) | 2015-04-28 | — | — | US | disclosed |
| US-7989478-B2 | decreases expression of a Type I collage gene in a tissue to induce a reduction in accumulation of collagen and thereby improves tissue fibrosis | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-02 | — | — | US | disclosed |