SCHEMBL16590761

SCHEMBL16590761

FC(F)=Cc1cccc(C=C(F)F)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 2/20 0.39
SLC9A1 P19634 1/20 0.38
SLC9A3 P48764 1/20 0.38
SLC9A2 Q9UBY0 1/20 0.38
POLB P06746 1/20 0.38
PTGS1 P23219 3/20 0.37
FBP1 P09467 2/20 0.37
FURIN P09958 1/20 0.37
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
PKM P14618 1/20 0.34
MAPK1 P28482 1/20 0.34
THPO P40225 1/20 0.34
NPC1 O15118 1/20 0.34
CHRM5 P08912 1/20 0.34
GRM5 P41594 1/20 0.34
RAB9A P51151 1/20 0.34
BLM P54132 1/20 0.34
PMP22 Q01453 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2283814 0.89 UNG (0.48) SLC9A1SLC9A3SLC9A2FBP1RAB9A
SCHEMBL12374676 0.89 TP53 (0.48) NFE2L2SLC9A1SLC9A3SLC9A2POLB
SCHEMBL19056944 0.87 TRIM24 (0.40) NFE2L2PTGS1FBP1CYP3A4
SCHEMBL2279404 0.84 ALDH1A1 (0.54) POLBCYP2D6
SCHEMBL4667870 0.84 TP53 (0.54) PTGS1FBP1CYP1A2MAPK1NPC1
SCHEMBL17288928 0.84 FBP1 (0.36) NFE2L2SLC9A1SLC9A3SLC9A2PTGS1
SCHEMBL30804566 0.84 TP53 (0.54) PTGS1FBP1CYP1A2MAPK1NPC1
SCHEMBL466536 0.80 ALDH1A1 (0.46) NFE2L2FBP1CYP3A4
SCHEMBL25371846 0.79 ENPP2 (0.48) CYP3A4
SCHEMBL19214110 0.79 SLC9A1 (0.34) SLC9A1SLC9A3SLC9A2PTGS1FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9075327-B2 Imaging members and methods for making the same XEROX CORPORATION (US) 2015-07-07 US disclosed
US-9017907-B2 Flexible imaging members having externally plasticized imaging layer(s) XEROX CORPORATION (US) 2015-04-28 US disclosed
US-20150086914-A1 IMAGING MEMBERS AND METHODS FOR MAKING THE SAME XEROX CORPORATION (US) 2015-03-26 US disclosed