SCHEMBL12375033

SCHEMBL12375033

C=CC(=O)OCc1ccc(OC(=O)CCc2ccc(-c3ccc(CC(=O)C(=C)C)cc3)cc2)c(C)c1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.38
AKR1C3 P42330 13/20 0.35
AKR1C2 P52895 3/20 0.34
FFAR4 Q5NUL3 5/20 0.34
FFAR1 O14842 3/20 0.33
THRB P10828 1/20 0.33
AKR1C4 P17516 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12375023 0.85 THRB (0.44) FFAR1THRB
SCHEMBL12375057 0.85 THRB (0.44) FFAR1THRB
SCHEMBL12375051 0.84 PPARD (0.35) AKR1C3AKR1C2FFAR4FFAR1THRB
SCHEMBL12375035 0.81 THRB (0.47) L3MBTL1FFAR1THRB
SCHEMBL12375053 0.81 THRB (0.43) FFAR4FFAR1THRB
SCHEMBL12375024 0.75 THRB (0.43) AKR1C3FFAR4FFAR1THRB
SCHEMBL13963239 0.75 MAOA (0.39)
SCHEMBL13963293 0.75 L3MBTL1 (0.32) L3MBTL1THRB
SCHEMBL10000384 0.74 L3MBTL1 (0.42) L3MBTL1AKR1C3FFAR4FFAR1THRB
SCHEMBL16541707 0.74 THRB (0.46) L3MBTL1FFAR1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8440101-B2 Liquid crystal composition containing polymerizable compound and liquid crystal display element using the same DIC CORPORATION (JP) 2013-05-14 US disclosed
US-20110186776-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2011-08-04 US disclosed