Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.53 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 2/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.47 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1236881 | 1.00 | HPGD (0.56) | HPGDSMN1; SMN2LMNAEPHX1NPSR1 | |
| SCHEMBL1237682 | 1.00 | HPGD (0.56) | HPGDSMN1; SMN2LMNAEPHX1NPSR1 | |
| SCHEMBL1236882 | 1.00 | HPGD (0.56) | HPGDSMN1; SMN2LMNAEPHX1NPSR1 | |
| SCHEMBL5408092 | 0.90 | EPHX2 (0.54) | — | |
| SCHEMBL30100538 | 0.90 | HPGD (0.47) | HPGDSMN1; SMN2LMNAEPHX1NPSR1 | |
| SCHEMBL5408085 | 0.90 | EPHX2 (0.54) | — | |
| SCHEMBL5413708 | 0.90 | EPHX2 (0.54) | — | |
| SCHEMBL5413720 | 0.90 | EPHX2 (0.54) | — | |
| SCHEMBL5413712 | 0.90 | EPHX2 (0.54) | — | |
| SCHEMBL30100510 | 0.87 | HPGD (0.44) | HPGDSMN1; SMN2LMNAEPHX1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820146-B2 | Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form | L'OREAL S.A. (FR) | 2010-10-26 | — | — | US | claimed |
| US-20050245673-A1 | Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form | L'OREAL S.A. (FR) | 2005-11-03 | — | — | US | claimed |
| US-20040223987-A1 | Composition structured with a polymer containing a heteroatom and organogelator | L'OREAL S.A. (FR) | 2004-11-11 | — | — | US | claimed |
| EP-1068854-B1 | Solid form composition comprising an oil and a specific gelling agent, process for cosmetic treatment and use of this compound | OREAL (FR) | 2004-08-18 | — | — | EP | claimed |
| WO-2002047628-A1 | COMPOSITION STRUCTURED WITH A POLYMER CONTAINING A HETEROATOM AND AN ORGANOGELATOR | L'ORÉAL (FR) | 2002-06-20 | — | — | WO | claimed |
| US-6372235-B1 | Compositions in solid form comprising an oil and a specific gelling compound, cosmetic treatment processes, and use of the compound | L'OREAL, S.A. (FR) | 2002-04-16 | — | — | US | claimed |
| EP-1068854-A1 | Solid form composition comprising an oil and a specific gelling agent, process for cosmetic treatment and use of this compound | L'OREAL (FR) | 2001-01-17 | — | — | EP | claimed |
| EP-1676556-B1 | Cosmetic composition containing a polyorganosiloxane polymer | OREAL (FR) | 2012-01-11 | — | — | EP | disclosed |
| US-20110189117-A1 | COSMETIC COMPOSITION CONTAINING A POLYORGANISILOXANE POLYMER | L'OREAL (FR) | 2011-08-04 | — | — | US | disclosed |
| US-7879316-B2 | Mixture of polyamide-siloxane copolymer in volatile oil; cosmetics | L'OREAL (FR) | 2011-02-01 | — | — | US | disclosed |
| US-7820146-B2 | Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form | L'OREAL S.A. (FR) | 2010-10-26 | — | — | US | disclosed |
| US-7803356-B2 | Compositions containing at least one silicone resin and a volatile non-cyclic silicone oil | L'OREAL (FR) | 2010-09-28 | — | — | US | disclosed |
| US-7758848-B2 | Cosmetic composition containing a polyorganosiloxane polymer | L'OREAL (FR) | 2010-07-20 | — | — | US | disclosed |
| US-20040170586-A1 | Cosmetic composition containing a polyorganosiloxane polymer | L'OREAL (FR) | 2004-09-02 | — | — | US | disclosed |
| EP-1068854-B1 | Solid form composition comprising an oil and a specific gelling agent, process for cosmetic treatment and use of this compound | OREAL (FR) | 2004-08-18 | — | — | EP | disclosed |
| US-20030091520-A1 | Use of at least one polar additive in a cosmetic composition comprising a liquid fatty phase structured by at least one molecular organogelator, to impart a thixotropic character to the composition | L'OREAL (FR) | 2003-05-15 | — | — | US | disclosed |
| EP-1264589-A1 | Use of a polar additive in a cosmetic composition containing a structured liquid oil phase by at least one organogelator to give a thixotropic character | L'OREAL (FR) | 2002-12-11 | — | — | EP | disclosed |
| WO-2002047628-A1 | COMPOSITION STRUCTURED WITH A POLYMER CONTAINING A HETEROATOM AND AN ORGANOGELATOR | L'ORÉAL (FR) | 2002-06-20 | — | — | WO | disclosed |
| US-6372235-B1 | Compositions in solid form comprising an oil and a specific gelling compound, cosmetic treatment processes, and use of the compound | L'OREAL, S.A. (FR) | 2002-04-16 | — | — | US | disclosed |
| EP-1068854-A1 | Solid form composition comprising an oil and a specific gelling agent, process for cosmetic treatment and use of this compound | L'OREAL (FR) | 2001-01-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040223987-A1 | Composition structured with a polymer containing a heteroatom and organogelator | CUTA, PARG, FABP4 | HPGD 471/4885SMN1; SMN2 3493/4885LMNA 1848/4885 |
| US-20040170586-A1 | Cosmetic composition containing a polyorganosiloxane polymer | CUTA, XPA, PRDX1 | HPGD 312/4885SMN1; SMN2 2953/4885LMNA 3883/4885 |
| US-20110189117-A1 | COSMETIC COMPOSITION CONTAINING A POLYORGANISILOXANE POLYMER | CUTA, PRDX1, PRXL2A | HPGD 504/4885SMN1; SMN2 1956/4885LMNA 4087/4885 |
| US-20030091520-A1 | Use of at least one polar additive in a cosmetic composition comprising a liquid fatty phase structured by at least one molecular organogelator, to impart a thixotropic character to the composition | PLIN3, CUTA, FABP4 | HPGD 2166/4885SMN1; SMN2 4783/4885LMNA 2968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.