Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 5/20 | 0.35 |
| ▸ | THRA | P10827 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12376845 | 0.81 | ALDH1A1 (0.37) | CYP1A2CYP2D6MAPK1ALDH1A1HSD17B10 | |
| SCHEMBL14572673 | 0.81 | ALDH1A1 (0.38) | CYP1A2CYP2D6MAPK1ALDH1A1HSD17B10 | |
| SCHEMBL9694125 | 0.79 | ALDH1A1 (0.37) | CYP1A2ALDH1A1HSD17B10HPGDL3MBTL1 | |
| SCHEMBL9694402 | 0.78 | L3MBTL1 (0.40) | CYP1A2MAPK1ALDH1A1HSD17B10HPGD | |
| SCHEMBL9694885 | 0.76 | ALDH1A1 (0.39) | CYP1A2CYP2D6ALDH1A1HSD17B10HPGD | |
| SCHEMBL9694565 | 0.76 | ALDH1A1 (0.39) | CYP1A2MAPK1ALDH1A1HSD17B10HPGD | |
| SCHEMBL9694960 | 0.74 | L3MBTL1 (0.42) | CYP1A2MAPK1ALDH1A1HSD17B10HPGD | |
| SCHEMBL9694779 | 0.71 | ALDH1A1 (0.38) | CYP1A2CYP2D6ALDH1A1HSD17B10HPGD | |
| SCHEMBL9692922 | 0.71 | TP53 (0.39) | CYP1A2MAPK1ALDH1A1HSD17B10HPGD | |
| SCHEMBL9694177 | 0.70 | HSPA5 (0.46) | CYP1A2CYP2D6MAPK1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10160732-B2 | MIF inhibitors | MIFCARE (FR) | 2018-12-25 | — | — | US | claimed |
| EP-2929882-B1 | MIF inhibitors | MIFCARE (FR) | 2018-06-13 | — | — | EP | claimed |
| US-20170029387-A1 | MIF INHIBITORS | APAXEN (BE) | 2017-02-02 | — | — | US | claimed |
| WO-2015155358-A1 | MIF INHIBITORS | MIFCARE (FR) | 2015-10-15 | — | — | WO | claimed |
| EP-2929882-A1 | MIF inhibitors | Mifcare (FR) | 2015-10-14 | — | — | EP | claimed |
| US-10160732-B2 | MIF inhibitors | MIFCARE (FR) | 2018-12-25 | — | — | US | disclosed |
| EP-2929882-B1 | MIF inhibitors | MIFCARE (FR) | 2018-06-13 | — | — | EP | disclosed |
| US-20170029387-A1 | MIF INHIBITORS | APAXEN (BE) | 2017-02-02 | — | — | US | disclosed |
| WO-2015155358-A1 | MIF INHIBITORS | MIFCARE (FR) | 2015-10-15 | — | — | WO | disclosed |
| EP-2929882-A1 | MIF inhibitors | Mifcare (FR) | 2015-10-14 | — | — | EP | disclosed |
| EP-1468331-B1 | POLYMERIC MATERIAL CONTAINING A LATENT ACID | BASF SE (DE) | 2012-10-03 | — | — | EP | disclosed |
| US-8003297-B2 | Polymeric material, containing a latent acid | BASF SE (DE) | 2011-08-23 | — | — | US | disclosed |
| US-20090155716-A1 | Polymeric material containing a latent acid, i.e. a compound which is not an acid but which can be converted to an acid by the influence of laser irradiation | HENEGHAN MICHAEL | 2009-06-18 | — | — | US | disclosed |
| EP-1407322-B1 | LASER MARKING METHOD | CIBA HOLDING INC (CH) | 2008-12-17 | — | — | EP | disclosed |
| US-7264916-B2 | Laser marking method | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-09-04 | — | — | US | disclosed |
| US-7264916-B2 | Laser marking method | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-09-04 | — | — | US | disclosed |
| US-7198884-B2 | Heat stable photocurable resin composition for dry film resist | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-04-03 | — | — | US | disclosed |
| US-7198884-B2 | Heat stable photocurable resin composition for dry film resist | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-04-03 | — | — | US | disclosed |
| US-20070054220-A1 | Polymeric material, containing a latent acid | HENEGHAN MICHAEL | 2007-03-08 | — | — | US | disclosed |
| US-20070054220-A1 | Polymeric material, containing a latent acid | HENEGHAN MICHAEL | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10160732-B2 | MIF inhibitors | MIF, MSR1, MMP12 | CYP1A2 1109/4885CYP2D6 1580/4885MAPK1 914/4885 |
| US-20170029387-A1 | MIF INHIBITORS | MIF, MSR1, MMP12 | CYP1A2 1109/4885CYP2D6 1580/4885MAPK1 914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.