SCHEMBL9694960

SCHEMBL9694960

Cc1cc(Cn2c(=S)sc3ccccc32)cc(C)c1O

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 1/20 0.42
PKM P14618 1/20 0.42
ALDH1A1 P00352 3/20 0.41
CYP1A2 P05177 1/20 0.41
HPGD P15428 1/20 0.41
HSD17B10 Q99714 1/20 0.41
LMNA P02545 2/20 0.40
TSHR P16473 1/20 0.40
HTT P42858 1/20 0.40
MAPK1 P28482 2/20 0.39
GAA P10253 2/20 0.39
POLB P06746 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
TP53 P04637 1/20 0.38
DRD2 P14416 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9694913 0.89 L3MBTL1 (0.39) L3MBTL1KDM4EPKMALDH1A1CYP1A2
SCHEMBL9694390 0.89 F2R (0.39) L3MBTL1KDM4EPKMALDH1A1CYP1A2
SCHEMBL9694765 0.86 ALOX5 (0.42) L3MBTL1KDM4EPKMALDH1A1CYP1A2
SCHEMBL9694539 0.83 L3MBTL1 (0.46) L3MBTL1KDM4EPKMALDH1A1CYP1A2
SCHEMBL9694402 0.83 L3MBTL1 (0.40) L3MBTL1KDM4EPKMALDH1A1CYP1A2
SCHEMBL9694157 0.83 TSHR (0.54) L3MBTL1KDM4EPKMALDH1A1CYP1A2
SCHEMBL9694360 0.83 F2R (0.43) L3MBTL1KDM4EPKMALDH1A1CYP1A2
SCHEMBL9694885 0.83 ALDH1A1 (0.39) L3MBTL1KDM4EPKMALDH1A1CYP1A2
SCHEMBL9694565 0.83 ALDH1A1 (0.39) L3MBTL1KDM4EPKMALDH1A1CYP1A2
SCHEMBL9694747 0.81 L3MBTL1 (0.43) L3MBTL1KDM4EPKMALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5169950-A Reacting a 2-mercaptobenzothiazole, acarbonyl and a phenol; basic catalyst; polar solvent CIBA-GEIGY CORPORATION (US) 1992-12-08 US disclosed
US-5097039-A Coating, lubricants CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
US-5069805-A OIL ADDITIVES CIBA-GEIGY CORPORATION (US) 1991-12-03 US disclosed
EP-0259254-B1 PHENOLIC BENZOTHIAZOLE DERIVATIVES AND THEIR USE AS CORROSION INHIBITORS CIBA-GEIGY AG (CH) 1991-04-17 EP disclosed
US-4894091-A PROTECTIVE COATINGS, PHOTOSTABILIZERS, HEAT RESISTANCE CIBA-GEIGY CORPORATION (US) 1990-01-16 US disclosed