SCHEMBL12376965

SCHEMBL12376965

COc1ccc(Cc2ccc(OC(=O)c3ccc(Oc4ccc(C(C)=O)cc4)cc3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 10/20 0.54
▸ MAPT P10636 4/20 0.54
▸ HPGD P15428 1/20 0.54
▸ RAB9A P51151 1/20 0.54
▸ LMNA P02545 2/20 0.51
▸ CYP1A2 P05177 1/20 0.51
▸ CYP2C9 P11712 1/20 0.51
▸ CYP2C19 P33261 1/20 0.51
▸ SMN1; SMN2 Q16637 1/20 0.51
▸ MEN1 O00255 1/20 0.50
▸ ALDH1A1 P00352 1/20 0.50
▸ GLA P06280 1/20 0.49
▸ TSHR P16473 1/20 0.49
▸ GFER P55789 1/20 0.49
▸ PRSS1 P07477 1/20 0.49
▸ ACR P10323 1/20 0.49
▸ SRD5A2 P31213 1/20 0.48
▸ PARP10 Q53GL7 1/20 0.47
▸ CA1 P00915 1/20 0.47
▸ CA2 P00918 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12762440 0.96 KMT2A (0.59) KMT2AMAPTRAB9ALMNACYP1A2
SCHEMBL12895879 0.96 KMT2A (0.59) KMT2AMAPTRAB9ALMNACYP1A2
SCHEMBL19763411 0.91 MAPT (0.66) KMT2AMAPTHPGDRAB9ALMNA
SCHEMBL12376956 0.91 MAPT (0.66) KMT2AMAPTHPGDRAB9ALMNA
SCHEMBL12376950 0.91 MAPT (0.66) KMT2AMAPTHPGDRAB9ALMNA
SCHEMBL11911280 0.91 MAPT (0.66) KMT2AMAPTHPGDRAB9ALMNA
SCHEMBL12404359 0.89 LMNA (0.46) KMT2AMAPTHPGDRAB9ALMNA
SCHEMBL13084494 0.88 KMT2A (0.56) KMT2AMAPTLMNACYP1A2CYP2C9
SCHEMBL12903847 0.88 L3MBTL1 (0.50) KMT2AMAPTHPGDRAB9ALMNA
SCHEMBL12376955 0.87 MAPT (0.59) KMT2AMAPTHPGDRAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9746816-B2 Image forming apparatus and electrophotographic cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2017-08-29 — — US disclosed
US-20170205719-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2017-07-20 — — US disclosed
US-20110206411-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2011-08-25 — — US disclosed
US-7985522-B2 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2011-07-26 — — US disclosed
US-7604913-B2 Electrophotographic photosensitive body MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-20 — — US disclosed
US-20090047589-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-19 — — US disclosed
US-20080063963-A1 Electrophotographic Photosensitive Body MITSUBISHI CHEMICAL CORPORATION (JP) 2008-03-13 — — US disclosed
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