SCHEMBL12762440

SCHEMBL12762440

COc1ccc(Cc2ccc(OC(=O)c3ccc(Cc4ccc(C(C)=O)cc4)cc3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 11/20 0.59
▸ LMNA P02545 3/20 0.55
▸ SMN1; SMN2 Q16637 2/20 0.55
▸ CYP1A2 P05177 1/20 0.55
▸ CYP2C9 P11712 1/20 0.55
▸ CYP2C19 P33261 1/20 0.55
▸ MAPT P10636 6/20 0.54
▸ ALDH1A1 P00352 2/20 0.54
▸ MEN1 O00255 1/20 0.54
▸ GLA P06280 1/20 0.52
▸ TSHR P16473 1/20 0.52
▸ GFER P55789 1/20 0.52
▸ PRSS1 P07477 1/20 0.52
▸ ACR P10323 1/20 0.52
▸ CA1 P00915 1/20 0.51
▸ CA2 P00918 1/20 0.51
▸ SAE1 Q9UBE0 1/20 0.50
▸ UBA2 Q9UBT2 1/20 0.50
▸ NPC1 O15118 1/20 0.48
▸ RAB9A P51151 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12895879 1.00 KMT2A (0.59) KMT2ALMNASMN1; SMN2CYP1A2CYP2C9
SCHEMBL12376965 0.96 KMT2A (0.54) KMT2ALMNASMN1; SMN2CYP1A2CYP2C9
SCHEMBL13084494 0.92 KMT2A (0.56) KMT2ALMNASMN1; SMN2CYP1A2CYP2C9
SCHEMBL13324835 0.91 KMT2A (0.49) KMT2ALMNASMN1; SMN2CYP1A2CYP2C9
SCHEMBL18230893 0.91 KMT2A (0.49) KMT2ALMNASMN1; SMN2CYP1A2CYP2C9
SCHEMBL13324841 0.91 KMT2A (0.49) KMT2ALMNASMN1; SMN2CYP1A2CYP2C9
SCHEMBL5616579 0.90 KMT2A (0.73) KMT2ALMNASMN1; SMN2MAPTALDH1A1
SCHEMBL11911278 0.90 LMNA (0.66) KMT2ALMNASMN1; SMN2CYP1A2CYP2C9
SCHEMBL16573858 0.89 CA1 (0.68) KMT2ALMNASMN1; SMN2CYP1A2CYP2C9
SCHEMBL12404363 0.88 LMNA (0.49) KMT2ALMNASMN1; SMN2CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7901855-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2011-03-08 — — US disclosed
US-7875410-B2 capable opersistently exerting effect of mitigating contact stress with contact members and improved potential stability during repeated use; polycarbonates CANON KABUSHIKI KAISHA (JP) 2011-01-25 — — US disclosed
US-20100092208-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2010-04-15 — — US disclosed
US-20100092209-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2010-04-15 — — US disclosed
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