SCHEMBL1626237

SCHEMBL1626237

Cc1ccc(N(c2ccc(/C=C/c3ccccc3C)cc2)c2ccc(N(c3ccc(C)cc3)c3ccc(/C=C/c4ccccc4C)cc3)c3ccccc23)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 4/20 0.46
RAB9A P51151 3/20 0.44
KDM4E B2RXH2 2/20 0.44
APOBEC3A P31941 1/20 0.44
APOBEC3G Q9HC16 1/20 0.44
FGF23 Q9GZV9 1/20 0.43
APP P05067 3/20 0.41
RAD52 P43351 2/20 0.37
MEN1 O00255 1/20 0.37
NPC1 O15118 1/20 0.37
NSD2 O96028 1/20 0.37
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37
THRB P10828 1/20 0.37
PKM P14618 1/20 0.37
MAPK1 P28482 1/20 0.37
PPARG P37231 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14537277 0.89 RELA (0.44) NFE2L2RAB9AKDM4EAPOBEC3AAPOBEC3G
SCHEMBL2153287 0.89 RELA (0.44) NFE2L2RAB9AKDM4EAPOBEC3AAPOBEC3G
SCHEMBL14537271 0.89 RELA (0.44) NFE2L2RAB9AKDM4EAPOBEC3AAPOBEC3G
SCHEMBL12376973 0.88 NFE2L2 (0.54) NFE2L2RAB9AKDM4EAPOBEC3AAPOBEC3G
SCHEMBL14665754 0.88 NFE2L2 (0.54) NFE2L2RAB9AKDM4EAPOBEC3AAPOBEC3G
SCHEMBL14099255 0.88 APP (0.43) NFE2L2RAB9AKDM4EAPOBEC3AAPOBEC3G
SCHEMBL2782260 0.87 FGF23 (0.48) NFE2L2RAB9AKDM4EFGF23APP
SCHEMBL14537276 0.86 TRPM8 (0.46) NFE2L2RAB9AKDM4EFGF23APP
SCHEMBL14537301 0.85 RELA (0.41) NFE2L2RAB9AKDM4EAPOBEC3AAPOBEC3G
SCHEMBL13311202 0.84 APP (0.46) NFE2L2RAB9AKDM4EFGF23APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8355204-B2 Light-extraction layer of light-emitting device and organic electroluminescence element employing the same KABUSHIKI KAISHA TOSHIBA (JP) 2013-01-15 US disclosed
US-7928353-B2 Displaying device and lighting device employing organic electroluminescence element KABUSHIKI KAISHA TOSHIBA (JP) 2011-04-19 US disclosed
US-20100309098-A1 IMAGE DISPLAY APPARATUS USING ORGANIC EL DEVICE CANON KABUSHIKI KAISHA (JP) 2010-12-09 US disclosed
US-7786665-B2 Organic electroluminescent device having a diffraction grating for enhancing light extraction efficiency KABUSHIKI KAISHA TOSHIBA (JP) 2010-08-31 US disclosed
US-20090236962-A1 DISPLAYING DEVICE AND LIGHTING DEVICE EMPLOYING ORGANIC ELECTROLUMINESCENCE ELEMENT KABUSHIKI KAISHA TOSHIBA (JP) 2009-09-24 US disclosed
US-20090224660-A1 LIGHT-EXTRACTION LAYER OF LIGHT-EMITTING DEVICE AND ORGANIC ELECTROLUMINESCENCE ELEMENT EMPLOYING THE SAME KABUSHIKI KAISHA TOSHIBA (JP) 2009-09-10 US disclosed
US-20060192483-A1 Organic electroluminescent device KABUSHIKI KAISHA TOSHIBA (JP) 2006-08-31 US disclosed
US-20020180348-A1 ORGANIC ELECTROLUMINESCENT DEVICE WITH A DEFRACTION GRADING AND LUMINESCENT LAYER SAMSUNG DISPLAY CO., LTD. (KR) 2002-12-05 US disclosed
US-6476550-B1 Organic Electroluminescent device with a defraction grading and luminescent layer NEC CORPORATION (JP) 2002-11-05 US disclosed