SCHEMBL12376996

SCHEMBL12376996

COc1c(C)cc(Cc2cc(C)c(OC(=O)c3ccc(C(=O)Oc4ccccc4)cc3)c(C)c2)cc1C

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ SRD5A2 P31213 1/20 0.44
▸ MAPT P10636 8/20 0.44
▸ SMN1; SMN2 Q16637 2/20 0.43
▸ PARP10 Q53GL7 1/20 0.42
▸ NSD2 O96028 1/20 0.42
▸ PRSS1 P07477 1/20 0.42
▸ ACR P10323 1/20 0.42
▸ TMPRSS15 P98073 1/20 0.42
▸ KMT2A Q03164 6/20 0.41
▸ ALDH1A1 P00352 4/20 0.41
▸ TDP1 Q9NUW8 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ PKM P14618 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14125309 0.92 KMT2A (0.45) SRD5A2MAPTSMN1; SMN2KMT2AALDH1A1
SCHEMBL16573859 0.86 MAPT (0.46) MAPTKMT2AALDH1A1TDP1L3MBTL1
SCHEMBL13324847 0.86 KMT2A (0.46) MAPTSMN1; SMN2PRSS1ACRKMT2A
SCHEMBL15164083 0.85 KMT2A (0.46) MAPTKMT2AALDH1A1
SCHEMBL12376954 0.85 KMT2A (0.46) MAPTKMT2AALDH1A1
SCHEMBL15493960 0.84 MAPT (0.50) MAPTSMN1; SMN2PARP10NSD2PRSS1
SCHEMBL13018407 0.83 LOXL2 (0.46) MAPTSMN1; SMN2PRSS1ACRKMT2A
SCHEMBL12376957 0.82 MAPT (0.47) SRD5A2MAPTKMT2AALDH1A1L3MBTL1
SCHEMBL139355 0.82 KMT2A (0.39) MAPTSMN1; SMN2KMT2AALDH1A1PKM
SCHEMBL13865058 0.82 KMT2A (0.41) MAPTSMN1; SMN2KMT2AALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9746816-B2 Image forming apparatus and electrophotographic cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2017-08-29 — — US disclosed
US-20170205719-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2017-07-20 — — US disclosed
US-20160018746-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMATION DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2016-01-21 — — US disclosed
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 — — US disclosed
US-20110206411-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2011-08-25 — — US disclosed
US-20090232551-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING DEVICE USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-17 — — US disclosed
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