SCHEMBL139355

SCHEMBL139355

COc1c(C)cc(Cc2cc(C)c(OC(=O)c3ccc(C(=O)Oc4c(C)cc(Cc5cc(C)c(OC(=O)c6cccc(C(C)=O)c6)c(C)c5)cc4C)cc3)c(C)c2)cc1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 5/20 0.39
▸ MEN1 O00255 3/20 0.39
▸ CREBBP Q92793 1/20 0.39
▸ ALDH1A1 P00352 5/20 0.39
▸ MAPT P10636 5/20 0.39
▸ POLB P06746 2/20 0.39
▸ GFER P55789 1/20 0.39
▸ KDM4E B2RXH2 2/20 0.38
▸ HPGD P15428 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ PKM P14618 1/20 0.38
▸ NPC1 O15118 2/20 0.38
▸ MAOB P27338 3/20 0.38
▸ LMNA P02545 3/20 0.38
▸ GAA P10253 1/20 0.38
▸ CYP1A2 P05177 1/20 0.37
▸ CYP3A4 P08684 1/20 0.37
▸ CYP2C9 P11712 1/20 0.37
▸ CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13865058 0.97 KMT2A (0.41) KMT2AMEN1CREBBPALDH1A1MAPT
SCHEMBL12762425 0.97 ALDH1A1 (0.40) KMT2AMEN1CREBBPALDH1A1MAPT
SCHEMBL13018407 0.91 LOXL2 (0.46) KMT2AMEN1ALDH1A1MAPTPOLB
SCHEMBL15164083 0.91 KMT2A (0.46) KMT2AALDH1A1MAPTPOLBMAOB
SCHEMBL12376954 0.91 KMT2A (0.46) KMT2AALDH1A1MAPTPOLBMAOB
SCHEMBL14125309 0.87 KMT2A (0.45) KMT2AMEN1ALDH1A1MAPTPOLB
SCHEMBL12762428 0.85 MAPT (0.43) KMT2AMEN1CREBBPALDH1A1MAPT
SCHEMBL13865060 0.85 ESR1 (0.39) KMT2AMEN1CREBBPALDH1A1MAPT
SCHEMBL12376957 0.85 MAPT (0.47) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL16573859 0.84 MAPT (0.46) KMT2AMEN1ALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120058422-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, PROCESS FOR PRODUCING THE SAME, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD (JP) 2012-03-08 — — US disclosed
US-20090123854-A1 IMAGE FORMING METHOD KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-05-14 — — US disclosed
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