SCHEMBL13018407

SCHEMBL13018407

COC(=O)c1ccc(C(=O)Oc2c(C)cc(Cc3cc(C)c(OC(=O)c4cccc(C(=O)Oc5c(C)cc(Cc6cc(C)c(OC)c(C)c6)cc5C)c4)c(C)c3)cc2C)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LOXL2 Q9Y4K0 2/20 0.46
▸ CYP4F2 P78329 2/20 0.45
▸ CYP4A11 Q02928 2/20 0.45
▸ MAPT P10636 5/20 0.43
▸ RAB9A P51151 4/20 0.43
▸ SMN1; SMN2 Q16637 3/20 0.43
▸ ALDH1A1 P00352 2/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ LMNA P02545 2/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ PRSS1 P07477 1/20 0.42
▸ ACR P10323 1/20 0.42
▸ NPC1 O15118 2/20 0.41
▸ POLB P06746 1/20 0.41
▸ BLM P54132 1/20 0.41
▸ TSHR P16473 1/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ MEN1 O00255 1/20 0.40
▸ TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16573859 0.93 MAPT (0.46) LOXL2CYP4F2CYP4A11MAPTRAB9A
SCHEMBL139355 0.91 KMT2A (0.39) MAPTSMN1; SMN2ALDH1A1KDM4ELMNA
SCHEMBL13865058 0.91 KMT2A (0.41) LOXL2CYP4F2CYP4A11MAPTSMN1; SMN2
SCHEMBL13864971 0.91 LOXL2 (0.49) LOXL2CYP4F2CYP4A11MAPTRAB9A
SCHEMBL12762425 0.88 ALDH1A1 (0.40) LOXL2CYP4F2CYP4A11MAPTRAB9A
SCHEMBL14125309 0.88 KMT2A (0.45) MAPTSMN1; SMN2ALDH1A1LMNAL3MBTL1
SCHEMBL13864915 0.86 TDP1 (0.47) LOXL2CYP4F2CYP4A11MAPTRAB9A
SCHEMBL12376954 0.84 KMT2A (0.46) MAPTALDH1A1LMNAKMT2APOLB
SCHEMBL15164083 0.84 KMT2A (0.46) MAPTALDH1A1LMNAKMT2APOLB
SCHEMBL12376996 0.83 SRD5A2 (0.44) MAPTRAB9ASMN1; SMN2ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530123-B2 Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2013-09-10 — — US disclosed
US-8450032-B2 — — 2013-05-28 — — US disclosed
US-8404411-B2 Electrophotographic photoreceptor, image-forming apparatus, and electrophotographic cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2013-03-26 — — US disclosed
US-20100330474-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2010-12-30 — — US disclosed
US-20090208250-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-08-20 — — US disclosed
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